CD20-positive plasma cell myeloma with lymphoplasmacytoid appearance mimicking low-grade B-cell lymphoma

Shojiro Haji, Yasunobu Abe, Mariko Tsuda, Kosuke Toyoda, Ilseung Choi, Youko Suehiro, Motoaki Shiratsuchi, Junichi Kiyasu, Naokuni Uike

研究成果: ジャーナルへの寄稿記事

抄録

CD 20 positive myeloma with small lymphoplasmacytoid morphology is difficult to differentiate from mature B-cell lymphoma. A 71-year-old male was referred to our hospital because of osteolytic vertebral fractures and anemia. Urine was positive for Bence Jones protein, κ type. Bone marrow consisted of approximately 30% small lymphoplasmacytoid cells with scant cytoplasm, and these cells were positive for CD20, CD23 and CD138. FISH analysis revealed t(11;14)(CCND1/IGH). Myeloma with t(11;14) is closely associated with small lymphoplasmacytoid appearance and CD20 and CD23 expressions. The patient was diagnosed as having myeloma based on clinical and cytogenetic findings, and achieved VGPR (very good partial response) after treatment with lenalidomide.

元の言語英語
ページ(範囲)335-338
ページ数4
ジャーナル[Rinshō ketsueki] The Japanese journal of clinical hematology
56
発行部数3
DOI
出版物ステータス出版済み - 3 1 2015
外部発表Yes

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B-Cell Lymphoma
Multiple Myeloma
Non-Hodgkin's Lymphoma
Bence Jones Protein
Cytogenetics
Anemia
Cytoplasm
Bone Marrow
Urine
Therapeutics
lenalidomide

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

CD20-positive plasma cell myeloma with lymphoplasmacytoid appearance mimicking low-grade B-cell lymphoma. / Haji, Shojiro; Abe, Yasunobu; Tsuda, Mariko; Toyoda, Kosuke; Choi, Ilseung; Suehiro, Youko; Shiratsuchi, Motoaki; Kiyasu, Junichi; Uike, Naokuni.

:: [Rinshō ketsueki] The Japanese journal of clinical hematology, 巻 56, 番号 3, 01.03.2015, p. 335-338.

研究成果: ジャーナルへの寄稿記事

Haji, Shojiro ; Abe, Yasunobu ; Tsuda, Mariko ; Toyoda, Kosuke ; Choi, Ilseung ; Suehiro, Youko ; Shiratsuchi, Motoaki ; Kiyasu, Junichi ; Uike, Naokuni. / CD20-positive plasma cell myeloma with lymphoplasmacytoid appearance mimicking low-grade B-cell lymphoma. :: [Rinshō ketsueki] The Japanese journal of clinical hematology. 2015 ; 巻 56, 番号 3. pp. 335-338.
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abstract = "CD 20 positive myeloma with small lymphoplasmacytoid morphology is difficult to differentiate from mature B-cell lymphoma. A 71-year-old male was referred to our hospital because of osteolytic vertebral fractures and anemia. Urine was positive for Bence Jones protein, κ type. Bone marrow consisted of approximately 30{\%} small lymphoplasmacytoid cells with scant cytoplasm, and these cells were positive for CD20, CD23 and CD138. FISH analysis revealed t(11;14)(CCND1/IGH). Myeloma with t(11;14) is closely associated with small lymphoplasmacytoid appearance and CD20 and CD23 expressions. The patient was diagnosed as having myeloma based on clinical and cytogenetic findings, and achieved VGPR (very good partial response) after treatment with lenalidomide.",
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T1 - CD20-positive plasma cell myeloma with lymphoplasmacytoid appearance mimicking low-grade B-cell lymphoma

AU - Haji, Shojiro

AU - Abe, Yasunobu

AU - Tsuda, Mariko

AU - Toyoda, Kosuke

AU - Choi, Ilseung

AU - Suehiro, Youko

AU - Shiratsuchi, Motoaki

AU - Kiyasu, Junichi

AU - Uike, Naokuni

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