Cell deformability measurements for single cancer cells by ionic current in microfluidic devices

Mamiko Sano, Noritada Kaji, Takao Yasui, Yoshinobu Baba

研究成果: 書籍/レポート タイプへの寄稿会議への寄与

抄録

To realize high-throughput, easy to use, and high-accuracy cell deformability measurements, we have developed ionic current detection system combined with constriction structure inside microchannel. In this system, when cells are clogged in constriction, the resistivity of detection area increases and the current decreases by ionic current blockade. We successfully detected unique signal shapes derived from cell deformability during the cell passage at the constriction. The signal shapes might provide an information on cell deformation and nucleus position inside a cell.

本文言語英語
ホスト出版物のタイトルMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
出版社Chemical and Biological Microsystems Society
ページ455-457
ページ数3
ISBN(電子版)9780979806483
出版ステータス出版済み - 2015
外部発表はい
イベント19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, 韓国
継続期間: 10月 25 201510月 29 2015

出版物シリーズ

名前MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

その他

その他19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
国/地域韓国
CityGyeongju
Period10/25/1510/29/15

!!!All Science Journal Classification (ASJC) codes

  • 制御およびシステム工学

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