TY - GEN
T1 - Cell fatigue test
AU - Fukui, W.
AU - Kaneko, M.
AU - Sakuma, S.
AU - Arai, F.
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - A new concept of 'Cell Fatigue Test' is proposed. By reciprocating a cell across the throat of a micro channel repeatedly, the dynamic behavior of cell deformation is measured. We define a new index of fatigue life of cells as the number of reciprocatory motions leading to the prescribed recovery ratio. The test system is composed of a piezoelectric (PZT) actuator, a high speed vision sensor and a micro channel with a throat. Preliminary experiments were conducted by using Red Blood Cells (RBCs). The result shows that there is great variability in fatigue life of cells and the hues of cell membrane drastically change as the number of stress cycles increase.
AB - A new concept of 'Cell Fatigue Test' is proposed. By reciprocating a cell across the throat of a micro channel repeatedly, the dynamic behavior of cell deformation is measured. We define a new index of fatigue life of cells as the number of reciprocatory motions leading to the prescribed recovery ratio. The test system is composed of a piezoelectric (PZT) actuator, a high speed vision sensor and a micro channel with a throat. Preliminary experiments were conducted by using Red Blood Cells (RBCs). The result shows that there is great variability in fatigue life of cells and the hues of cell membrane drastically change as the number of stress cycles increase.
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U2 - 10.1109/MEMSYS.2013.6474423
DO - 10.1109/MEMSYS.2013.6474423
M3 - Conference contribution
AN - SCOPUS:84875449496
SN - 9781467356558
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 1025
EP - 1028
BT - IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
T2 - IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Y2 - 20 January 2013 through 24 January 2013
ER -