Cell Kinetics of Intracerebrally Implanted RG-C6 Tumors in Rats: Effects of Intracarotid Hyperosmolar Mannitol measured by 3H-thymidine Autoradiography and Bromodeoxyuridine Uptake

Tooru Inoue, Masashi Fukui, Iwao Takeshita, Toru Iwaki

研究成果: Contribution to journalArticle査読

抄録

The proliferative activity of intracerebrally implanted rat glioma C6 (RG-C6) tumors in rats was exam ined by means of 3H-thymidine autoradiography and measurement of bromodeoxyuridine (BrdU) uptake. The effect of intracarotid hyperosmolar mannitol on the cell kinetics of the RG-C6 tumors was studied by the latter method. The labeling index (LI) and distribution of 3H-thymidine-labeled cells were identical to those of the BrdU-labeled cells. The LIs of BrdU-labeled cells were not altered by in tracarotid mannitol injection. The influence of intracarotid hyperosmolar mannitol infusion not only on brain tumors but also on normal brain tissue is discussed.

本文言語英語
ページ(範囲)533-537
ページ数5
ジャーナルNeurologia medico-chirurgica
28
6
DOI
出版ステータス出版済み - 1988

All Science Journal Classification (ASJC) codes

  • 外科
  • 臨床神経学

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「Cell Kinetics of Intracerebrally Implanted RG-C6 Tumors in Rats: Effects of Intracarotid Hyperosmolar Mannitol measured by <sup>3</sup>H-thymidine Autoradiography and Bromodeoxyuridine Uptake」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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