Cellular and molecular abnormalities in the vascular endothelium of diabetes mellitus

George L. King, Teruo Shiba, Javier Oliver, Toyoshi Inoguchi, Sven Erik Bursell

    研究成果: Contribution to journalReview article査読

    125 被引用数 (Scopus)

    抄録

    Diabetic vascular complications affect both micro- and macrovasculature, primarily in the retina, renal glomeruli, and multiple sites in the macrovessels. This review presents a summary of the abnormal function found in vivo and in cultured vascular cells exposed to elevated levels of glucose. We also discuss the various biochemical hypotheses that have been proposed to explain the adverse effects of hyperglycemia on vascular cells.

    本文言語英語
    ページ(範囲)179-188
    ページ数10
    ジャーナルAnnual review of medicine
    45
    DOI
    出版ステータス出版済み - 1994

    All Science Journal Classification (ASJC) codes

    • 生化学、遺伝学、分子生物学(全般)

    フィンガープリント

    「Cellular and molecular abnormalities in the vascular endothelium of diabetes mellitus」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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