Cerebral blood flow, oxygen and glucose metabolism with PET in progressive supranuclear palsy

Makoto Otsuka; Yuichi Ichiya; Yasuo Kuwabara; Yoshinori Miyake; Takashi Tahara; Kouji Masuda; Shinichi Hosokawa; Ikuo Goto; Motohiro Kato; Atsushi Ichimiya; Motohiro Suetsugu

doi:10.1007/BF03178296

Cerebral blood flow, oxygen and glucose metabolism with PET in progressive supranuclear palsy

Makoto Otsuka, Yuichi Ichiya, Yasuo Kuwabara, Yoshinori Miyake, Takashi Tahara, Kouji Masuda, Shinichi Hosokawa, Ikuo Goto, Motohiro Kato, Atsushi Ichimiya, Motohiro Suetsugu

キャンパスライフ・健康支援センター

研究成果: Contribution to journal › Article › 査読

27 被引用数 (Scopus)

抄録

Cerebral blood flow, cerebral oxygen metabolic rate and cerebral glucose metabolic rate were measured with positron emission tomography (PET) in four patients with progressive supranuclear palsy (PSP). Decreased blood flow and hypometabolism of oxygen and glucose were found in both subcortical and cortical regions, particularly in the striatum including the head of the caudate nucleus and the frontal cortex. The coupling between blood flow and metabolism was preserved even in the regions which showed decreased blood flow and hypometabolism. These findings indicated the hypofunction, as revealed by decreased blood flow and hypometabolism on PET, both in the striatum and the frontal cortex, and which may underlie the pathophysiological mechanism of motor and mental disturbance in PSP.

本文言語	英語
ページ（範囲）	111-118
ページ数	8
ジャーナル	Annals of Nuclear Medicine
巻	3
号	3
DOI	https://doi.org/10.1007/BF03178296
出版ステータス	出版済み - 12 1 1989

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

文献へのアクセス

10.1007/BF03178296

フィンガープリント「Cerebral blood flow, oxygen and glucose metabolism with PET in progressive supranuclear palsy」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル

Cerebral blood flow, oxygen and glucose metabolism with PET in progressive supranuclear palsy. / Otsuka, Makoto; Ichiya, Yuichi; Kuwabara, Yasuo; Miyake, Yoshinori; Tahara, Takashi; Masuda, Kouji; Hosokawa, Shinichi; Goto, Ikuo; Kato, Motohiro; Ichimiya, Atsushi; Suetsugu, Motohiro.

In: Annals of Nuclear Medicine, Vol. 3, No. 3, 01.12.1989, p. 111-118.

研究成果: Contribution to journal › Article › 査読

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AU - Masuda, Kouji

AU - Hosokawa, Shinichi

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