Vibratory perception threshold (VPT) in diabetic patients (NIDDM) with (n=13) or without neuropathy (n=12) and age matched control subjects (n=12) was measured at the right internal malleolus using a vibratory perception meter (TM-31A). After continuous vibratory stimulation at 150 μm amplitude for 5 min, VPT was again measured at 0, 2 and 5 min. VPT in the three groups was significantly increased after the stimulation. VPT was significantly higher in both groups of diabetic patients than in controls at 0, 2 and 5 min after the stimulation. Additionaly, the increment in VPT from before to after the stimulation (at 0 min) showed significantly positive correlations with FPG and HbA1c level, suggesting that the change in VPT after the stimulation may be related with glycemic control in diabetic patients. The measurement of VPT after continuous vibratory stimulation with a TM-31A revealed abnormal peripheral nerve function in diabetic patients who had no clinical neuropathy.
All Science Journal Classification (ASJC) codes
- Internal Medicine
- Endocrinology, Diabetes and Metabolism