Class IIa bacteriocins: Biosynthesis, structure and activity

Saïd Ennahar, Toshihiro Sashihara, Kenji Sonomoto, Ayaaki Ishizaki

研究成果: Contribution to journalReview article

445 引用 (Scopus)

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In the last decade, a variety of ribosomally synthesized antimicrobial peptides or bacteriocins produced by lactic acid bacteria have been identified and characterized. As a result of these studies, insight has been gained into fundamental aspects of biology and biochemistry such as producer self protection, membrane-protein interactions, and protein modification and secretion. Moreover, it has become evident that these peptides may be developed into useful antimicrobial additives. Class IIa bacteriocins can be considered as the major subgroup of bacteriocins from lactic acid bacteria, not only because of their large number, but also because of their activities and potential applications. They have first attracted particular attention as listericidal compounds and are now believed to be the next in line if more bacteriocins are to be approved in the future. The present review attempts to provide an insight into general knowledge available for class IIa bacteriocins and discusses common features and recent findings concerning these substances.

元の言語英語
ページ(範囲)85-106
ページ数22
ジャーナルFEMS Microbiology Reviews
24
発行部数1
DOI
出版物ステータス出版済み - 1 1 2000

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Infectious Diseases

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