Clinical Features of Systemic Metastatic Retinal Lymphoma in Japanese Patients

Rumiko Taki, Atsunobu Takeda, Hiroshi Yoshikawa, Takako Fukuhara, Ryoichi Arita, Yoko Suehiro, Ilseung Choi, Yuji Kumano, Takao Nakamura, Tatsuro Ishibashi

研究成果: Contribution to journalArticle査読

1 被引用数 (Scopus)

抄録

Purpose: Systemic metastatic retinal lymphoma (SMRL) originates in systemic organs. It has been reported to exhibit clinical features similar to those of primary vitreoretinal lymphoma (PVRL). We report six cases of SMRL in a single-center survey in Japan. Methods: The clinical and pathologic features in SMRL at the Kyushu University Hospital were retrospectively studied. Results: The mean patient age at the onset of ocular involvement was 75.3 years. Four patients had brain involvement. The primary sites were: breast (2); chest (1); testis (1); intestinal tract (1); and nasal sinus (1). In all patients, the cytology of vitreous samples indicated diffuse large B-cell lymphoma (DLBCL). Conclusions: DLBCL is the most common subtype in our study. The prevalence of CNS involvement in patients with SMRL is similar to that with PVRL. The testis and breast may be common sites of origin for SMRL.

本文言語英語
ページ(範囲)654-662
ページ数9
ジャーナルOcular Immunology and Inflammation
25
5
DOI
出版ステータス出版済み - 9 3 2017

All Science Journal Classification (ASJC) codes

  • 免疫アレルギー学
  • 眼科学

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