Clinical outcomes of Clutch Cutter endoscopic submucosal dissection for older patients with early gastric cancer

Yoshihiro Otsuka, Kazuya Akahoshi, Kayoko Yasunaga, Masaru Kubokawa, Junya Gibo, Shigeki Osada, Kayo Tokumaru, Kazuaki Miyamoto, Takao Sato, Yuki Shiratsuchi, Masafumi Oya, Hidenobu Koga, Eikichi Ihara, Kazuhiko Nakamura

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

抄録

AIM To evaluate the clinical outcome of endoscopic subSubmitmucosal dissection using the Clutch Cutter (ESDCC) in older patients. METHODS We reviewed 232 consecutive patients with early gastric cancer who underwent ESDCC between June 2010 and February 2014 at Aso Iizuka Hospital. We divided patients into two groups according to age: Older patients ( > 80 years, n = 64) and non-older patients (= 80 years, n = 168). We retrospectively compared the prevalence rates of pre-existing comorbidities, anticoagulant therapy, en bloc resection, mean duration of hospitalization, incidence of ESDCC-related complications, change in performance status (PS) before and after ESDCC, and financial cost of admission. RESULTS The older group comprised 64 patients with a mean age of 84.1 years, and the non-older group comprised 168 patients with a mean age of 69.5 years. Older patients had significantly more pre-existing comorbidities than did non-older patients, specifically heart disease (P < 0.05). The en bloc resection rate in non-older patients was significantly higher than that in older patients (100% vs 95.3%, P = 0.02). There were no significant differences between the older and non-older groups in the incidence of ESDCC-related complications (i.e., postoperative bleeding and perforation) and the post-ESDCC change in PS. There were also no significant differences between the older and non-older groups in the mean duration of hospitalization (11.4 and 10.7 d, respectively) and financial cost of admission (657040 JPY and 574890 JPY, respectively). CONCLUSION ESDCC has a good clinical outcome in older patients.

元の言語英語
ページ(範囲)416-422
ページ数7
ジャーナルWorld Journal of Gastrointestinal Oncology
9
発行部数10
DOI
出版物ステータス出版済み - 10 1 2017

Fingerprint

Stomach Neoplasms
Dissection
Endoscopic Mucosal Resection
Comorbidity
Hospitalization
Costs and Cost Analysis
Incidence
Anticoagulants
Heart Diseases
Hemorrhage

All Science Journal Classification (ASJC) codes

  • Oncology
  • Gastroenterology

これを引用

Clinical outcomes of Clutch Cutter endoscopic submucosal dissection for older patients with early gastric cancer. / Otsuka, Yoshihiro; Akahoshi, Kazuya; Yasunaga, Kayoko; Kubokawa, Masaru; Gibo, Junya; Osada, Shigeki; Tokumaru, Kayo; Miyamoto, Kazuaki; Sato, Takao; Shiratsuchi, Yuki; Oya, Masafumi; Koga, Hidenobu; Ihara, Eikichi; Nakamura, Kazuhiko.

:: World Journal of Gastrointestinal Oncology, 巻 9, 番号 10, 01.10.2017, p. 416-422.

研究成果: ジャーナルへの寄稿記事

Otsuka, Y, Akahoshi, K, Yasunaga, K, Kubokawa, M, Gibo, J, Osada, S, Tokumaru, K, Miyamoto, K, Sato, T, Shiratsuchi, Y, Oya, M, Koga, H, Ihara, E & Nakamura, K 2017, 'Clinical outcomes of Clutch Cutter endoscopic submucosal dissection for older patients with early gastric cancer', World Journal of Gastrointestinal Oncology, 巻. 9, 番号 10, pp. 416-422. https://doi.org/10.4251/wjgo.v9.i10.416
Otsuka, Yoshihiro ; Akahoshi, Kazuya ; Yasunaga, Kayoko ; Kubokawa, Masaru ; Gibo, Junya ; Osada, Shigeki ; Tokumaru, Kayo ; Miyamoto, Kazuaki ; Sato, Takao ; Shiratsuchi, Yuki ; Oya, Masafumi ; Koga, Hidenobu ; Ihara, Eikichi ; Nakamura, Kazuhiko. / Clinical outcomes of Clutch Cutter endoscopic submucosal dissection for older patients with early gastric cancer. :: World Journal of Gastrointestinal Oncology. 2017 ; 巻 9, 番号 10. pp. 416-422.
@article{cf0adde10b5f46e799b4e466b10bc8c3,
title = "Clinical outcomes of Clutch Cutter endoscopic submucosal dissection for older patients with early gastric cancer",
abstract = "AIM To evaluate the clinical outcome of endoscopic subSubmitmucosal dissection using the Clutch Cutter (ESDCC) in older patients. METHODS We reviewed 232 consecutive patients with early gastric cancer who underwent ESDCC between June 2010 and February 2014 at Aso Iizuka Hospital. We divided patients into two groups according to age: Older patients ( > 80 years, n = 64) and non-older patients (= 80 years, n = 168). We retrospectively compared the prevalence rates of pre-existing comorbidities, anticoagulant therapy, en bloc resection, mean duration of hospitalization, incidence of ESDCC-related complications, change in performance status (PS) before and after ESDCC, and financial cost of admission. RESULTS The older group comprised 64 patients with a mean age of 84.1 years, and the non-older group comprised 168 patients with a mean age of 69.5 years. Older patients had significantly more pre-existing comorbidities than did non-older patients, specifically heart disease (P < 0.05). The en bloc resection rate in non-older patients was significantly higher than that in older patients (100{\%} vs 95.3{\%}, P = 0.02). There were no significant differences between the older and non-older groups in the incidence of ESDCC-related complications (i.e., postoperative bleeding and perforation) and the post-ESDCC change in PS. There were also no significant differences between the older and non-older groups in the mean duration of hospitalization (11.4 and 10.7 d, respectively) and financial cost of admission (657040 JPY and 574890 JPY, respectively). CONCLUSION ESDCC has a good clinical outcome in older patients.",
author = "Yoshihiro Otsuka and Kazuya Akahoshi and Kayoko Yasunaga and Masaru Kubokawa and Junya Gibo and Shigeki Osada and Kayo Tokumaru and Kazuaki Miyamoto and Takao Sato and Yuki Shiratsuchi and Masafumi Oya and Hidenobu Koga and Eikichi Ihara and Kazuhiko Nakamura",
year = "2017",
month = "10",
day = "1",
doi = "10.4251/wjgo.v9.i10.416",
language = "English",
volume = "9",
pages = "416--422",
journal = "World Journal of Gastrointestinal Oncology",
issn = "1948-5204",
publisher = "Baishideng Publishing Group",
number = "10",

}

TY - JOUR

T1 - Clinical outcomes of Clutch Cutter endoscopic submucosal dissection for older patients with early gastric cancer

AU - Otsuka, Yoshihiro

AU - Akahoshi, Kazuya

AU - Yasunaga, Kayoko

AU - Kubokawa, Masaru

AU - Gibo, Junya

AU - Osada, Shigeki

AU - Tokumaru, Kayo

AU - Miyamoto, Kazuaki

AU - Sato, Takao

AU - Shiratsuchi, Yuki

AU - Oya, Masafumi

AU - Koga, Hidenobu

AU - Ihara, Eikichi

AU - Nakamura, Kazuhiko

PY - 2017/10/1

Y1 - 2017/10/1

N2 - AIM To evaluate the clinical outcome of endoscopic subSubmitmucosal dissection using the Clutch Cutter (ESDCC) in older patients. METHODS We reviewed 232 consecutive patients with early gastric cancer who underwent ESDCC between June 2010 and February 2014 at Aso Iizuka Hospital. We divided patients into two groups according to age: Older patients ( > 80 years, n = 64) and non-older patients (= 80 years, n = 168). We retrospectively compared the prevalence rates of pre-existing comorbidities, anticoagulant therapy, en bloc resection, mean duration of hospitalization, incidence of ESDCC-related complications, change in performance status (PS) before and after ESDCC, and financial cost of admission. RESULTS The older group comprised 64 patients with a mean age of 84.1 years, and the non-older group comprised 168 patients with a mean age of 69.5 years. Older patients had significantly more pre-existing comorbidities than did non-older patients, specifically heart disease (P < 0.05). The en bloc resection rate in non-older patients was significantly higher than that in older patients (100% vs 95.3%, P = 0.02). There were no significant differences between the older and non-older groups in the incidence of ESDCC-related complications (i.e., postoperative bleeding and perforation) and the post-ESDCC change in PS. There were also no significant differences between the older and non-older groups in the mean duration of hospitalization (11.4 and 10.7 d, respectively) and financial cost of admission (657040 JPY and 574890 JPY, respectively). CONCLUSION ESDCC has a good clinical outcome in older patients.

AB - AIM To evaluate the clinical outcome of endoscopic subSubmitmucosal dissection using the Clutch Cutter (ESDCC) in older patients. METHODS We reviewed 232 consecutive patients with early gastric cancer who underwent ESDCC between June 2010 and February 2014 at Aso Iizuka Hospital. We divided patients into two groups according to age: Older patients ( > 80 years, n = 64) and non-older patients (= 80 years, n = 168). We retrospectively compared the prevalence rates of pre-existing comorbidities, anticoagulant therapy, en bloc resection, mean duration of hospitalization, incidence of ESDCC-related complications, change in performance status (PS) before and after ESDCC, and financial cost of admission. RESULTS The older group comprised 64 patients with a mean age of 84.1 years, and the non-older group comprised 168 patients with a mean age of 69.5 years. Older patients had significantly more pre-existing comorbidities than did non-older patients, specifically heart disease (P < 0.05). The en bloc resection rate in non-older patients was significantly higher than that in older patients (100% vs 95.3%, P = 0.02). There were no significant differences between the older and non-older groups in the incidence of ESDCC-related complications (i.e., postoperative bleeding and perforation) and the post-ESDCC change in PS. There were also no significant differences between the older and non-older groups in the mean duration of hospitalization (11.4 and 10.7 d, respectively) and financial cost of admission (657040 JPY and 574890 JPY, respectively). CONCLUSION ESDCC has a good clinical outcome in older patients.

UR - http://www.scopus.com/inward/record.url?scp=85041750536&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85041750536&partnerID=8YFLogxK

U2 - 10.4251/wjgo.v9.i10.416

DO - 10.4251/wjgo.v9.i10.416

M3 - Article

VL - 9

SP - 416

EP - 422

JO - World Journal of Gastrointestinal Oncology

JF - World Journal of Gastrointestinal Oncology

SN - 1948-5204

IS - 10

ER -