Clinical significance of surgical resection of metastatic lymph nodes from hepatocellular carcinoma

Yoshito Tomimaru, Hiroshi Wada, Hidetoshi Eguchi, Akira Tomokuni, Naoki Hama, Koichi Kawamoto, Shigeru Marubashi, Koji Umeshita, Yuichiro Doki, Masaki Mori, Kenichi Wakasa, Hiroaki Nagano

研究成果: Contribution to journalArticle査読

17 被引用数 (Scopus)

抄録

Purpose: The clinical significance of the surgical resection of metastatic lymph nodes (LN) from patients with hepatocellular carcinoma (HCC) remains controversial. The aim of this study was to evaluate the significance of the surgical resection of LN metastasis of HCC. Methods: Among 961 patients who underwent surgical resection for HCC in our hospital, LN metastasis was identified in 38 patients. In these patients, the metastatic LN were removed completely in 22 patients (complete removal group), and incompletely or not removed in 16 patients (control group). The long-term prognosis after LN metastasis was compared between the two groups. Results: The overall survival rate after LN metastasis was significantly better in the complete removal group (1-, 3- and 5-year: 71.2, 58.0 and 49.7 %, respectively) than in the control group (45.9, 23.0 and 15.3 %, respectively, p = 0.0477). LN metastasis was not the cause of death in any of the patients in the complete removal group, whereas it was a cause in some patients in the control group. No local LN recurrence was identified in the complete removal group. Conclusions: The present results suggest that the complete removal of metastatic LN from HCC is clinically beneficial in selected patients.

本文言語英語
ページ(範囲)1112-1120
ページ数9
ジャーナルSurgery today
45
9
DOI
出版ステータス出版済み - 9 17 2015

All Science Journal Classification (ASJC) codes

  • Surgery

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