Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS

Yasunobu Yoshikai, Hiroyuki Kidokoro, Keiko Kimura, Yoshiyasu Aoki, Masahiko Makino, Kenji Hiromatsu

    研究成果: ジャーナルへの寄稿記事

    3 引用 (Scopus)

    抄録

    Subcutaneous injection of FK506 (10 mg/kg of body weight) completely blocked the clonal expansion of staphylococcal enterotoxin A (SEA)-reactive T cells in healthy (control) mice after SEA injection but did not disturb it in mice with murine AIDS (MAIDS) caused by infection with LP-BM5 murine leukemia virus. MAIDS mice are characterized by utilization of a FK506-insensitive pathway for clonal expansion of superantigen-reactive T cells.

    元の言語英語
    ページ(範囲)746-749
    ページ数4
    ジャーナルJournal of Virology
    71
    発行部数1
    出版物ステータス出版済み - 1 1 1997

    Fingerprint

    superantigens
    Superantigens
    Tacrolimus
    Murine Acquired Immunodeficiency Syndrome
    Acquired Immunodeficiency Syndrome
    T-lymphocytes
    T-Lymphocytes
    mice
    enterotoxins
    Murine Leukemia Viruses
    Subcutaneous Injections
    Murine leukemia virus
    Body Weight
    subcutaneous injection
    Injections
    Infection
    injection
    body weight
    Staphylococcal enterotoxin A
    infection

    All Science Journal Classification (ASJC) codes

    • Microbiology
    • Immunology
    • Insect Science
    • Virology

    これを引用

    Yoshikai, Y., Kidokoro, H., Kimura, K., Aoki, Y., Makino, M., & Hiromatsu, K. (1997). Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS. Journal of Virology, 71(1), 746-749.

    Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS. / Yoshikai, Yasunobu; Kidokoro, Hiroyuki; Kimura, Keiko; Aoki, Yoshiyasu; Makino, Masahiko; Hiromatsu, Kenji.

    :: Journal of Virology, 巻 71, 番号 1, 01.01.1997, p. 746-749.

    研究成果: ジャーナルへの寄稿記事

    Yoshikai, Y, Kidokoro, H, Kimura, K, Aoki, Y, Makino, M & Hiromatsu, K 1997, 'Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS', Journal of Virology, 巻. 71, 番号 1, pp. 746-749.
    Yoshikai Y, Kidokoro H, Kimura K, Aoki Y, Makino M, Hiromatsu K. Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS. Journal of Virology. 1997 1 1;71(1):746-749.
    Yoshikai, Yasunobu ; Kidokoro, Hiroyuki ; Kimura, Keiko ; Aoki, Yoshiyasu ; Makino, Masahiko ; Hiromatsu, Kenji. / Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS. :: Journal of Virology. 1997 ; 巻 71, 番号 1. pp. 746-749.
    @article{a2b281eb0e964046b276aab6be843bcd,
    title = "Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS",
    abstract = "Subcutaneous injection of FK506 (10 mg/kg of body weight) completely blocked the clonal expansion of staphylococcal enterotoxin A (SEA)-reactive T cells in healthy (control) mice after SEA injection but did not disturb it in mice with murine AIDS (MAIDS) caused by infection with LP-BM5 murine leukemia virus. MAIDS mice are characterized by utilization of a FK506-insensitive pathway for clonal expansion of superantigen-reactive T cells.",
    author = "Yasunobu Yoshikai and Hiroyuki Kidokoro and Keiko Kimura and Yoshiyasu Aoki and Masahiko Makino and Kenji Hiromatsu",
    year = "1997",
    month = "1",
    day = "1",
    language = "English",
    volume = "71",
    pages = "746--749",
    journal = "Journal of Virology",
    issn = "0022-538X",
    publisher = "American Society for Microbiology",
    number = "1",

    }

    TY - JOUR

    T1 - Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS

    AU - Yoshikai, Yasunobu

    AU - Kidokoro, Hiroyuki

    AU - Kimura, Keiko

    AU - Aoki, Yoshiyasu

    AU - Makino, Masahiko

    AU - Hiromatsu, Kenji

    PY - 1997/1/1

    Y1 - 1997/1/1

    N2 - Subcutaneous injection of FK506 (10 mg/kg of body weight) completely blocked the clonal expansion of staphylococcal enterotoxin A (SEA)-reactive T cells in healthy (control) mice after SEA injection but did not disturb it in mice with murine AIDS (MAIDS) caused by infection with LP-BM5 murine leukemia virus. MAIDS mice are characterized by utilization of a FK506-insensitive pathway for clonal expansion of superantigen-reactive T cells.

    AB - Subcutaneous injection of FK506 (10 mg/kg of body weight) completely blocked the clonal expansion of staphylococcal enterotoxin A (SEA)-reactive T cells in healthy (control) mice after SEA injection but did not disturb it in mice with murine AIDS (MAIDS) caused by infection with LP-BM5 murine leukemia virus. MAIDS mice are characterized by utilization of a FK506-insensitive pathway for clonal expansion of superantigen-reactive T cells.

    UR - http://www.scopus.com/inward/record.url?scp=0031060454&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=0031060454&partnerID=8YFLogxK

    M3 - Article

    C2 - 8985410

    AN - SCOPUS:0031060454

    VL - 71

    SP - 746

    EP - 749

    JO - Journal of Virology

    JF - Journal of Virology

    SN - 0022-538X

    IS - 1

    ER -