Cloning of a cDNA encoding a novel sugar transporter expressed in the neonatal mouse hippocampus

Naoki Matsuo, Shoko Kawamoto, Kenichi Matsubara, Kousaku Okubo

研究成果: Contribution to journalArticle査読

12 被引用数 (Scopus)

抄録

While analyzing active genes in the neonatal mouse hippocampus, we observed several novel genes that were abundantly expressed in this tissue. We report here cloning and sequencing of one of these tran scripts, HiAT1 (Hippocampus Abundant Gene Transcript 1). The mRNA was 2.7 Kb in length, and the deduced amino acid sequence consisted of 490 amino acids with characteristics typical of members of the sugar transporter family. However, its overall sequence homology to known transporter cDNAs was only about 30%, suggesting strongly that it represents a novel sugar transporter gene. Northern hybridization analyses showed this transcript is detected in adult and embryonic brains, as well as in other tissues.

本文言語英語
ページ(範囲)126-129
ページ数4
ジャーナルBiochemical and Biophysical Research Communications
238
1
DOI
出版ステータス出版済み - 9 8 1997
外部発表はい

All Science Journal Classification (ASJC) codes

  • 生物理学
  • 生化学
  • 分子生物学
  • 細胞生物学

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