COENZYME MODELS - 19. OXIDATION OF FUROIN BY A FLAVIN IMMOBILIZED IN CATIONIC POLYELECTROLYTES - A FLAVOENZYME MODEL.

Seiji Shinkai

研究成果: Contribution to journalArticle

1 引用 (Scopus)

抜粋

In the reported study, the rate constants for the oxidation of furoin by a flavin (vitamin B//2 analog) immobilized in catonic polymers were evaluated under anaerobic conditions, and the influence of reaction environments was discussed in connection with the enzymatic reactivity. It was found that (1) proton abstraction from furoin which forms the carbanionic intermediate is rate determining in the initial stage of the reaction and is facilitated by the environment of cationic polymers, (2) proton abstraction is efficiently accelerated by added cationic surfactant (CTAB), and (3) N-dodecylbenzohydroxamic acid in aqueous CTAB acts as an excellent proton-abstracting reagent. the polymers with high dodecyl group content served, in all cases, as better oxidizing reagents. As a summary of these conclusions, the importance of hydrophobic environments in flavin-mediated oxidation was emphasized.

元の言語英語
ページ(範囲)3905-3912
ページ数8
ジャーナルJournal of polymer science. Part A-1, Polymer chemistry
17
発行部数12
DOI
出版物ステータス出版済み - 1979

All Science Journal Classification (ASJC) codes

  • Engineering(all)

フィンガープリント COENZYME MODELS - 19. OXIDATION OF FUROIN BY A FLAVIN IMMOBILIZED IN CATIONIC POLYELECTROLYTES - A FLAVOENZYME MODEL.' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用