抄録
In the reported study, the rate constants for the oxidation of furoin by a flavin (vitamin B//2 analog) immobilized in catonic polymers were evaluated under anaerobic conditions, and the influence of reaction environments was discussed in connection with the enzymatic reactivity. It was found that (1) proton abstraction from furoin which forms the carbanionic intermediate is rate determining in the initial stage of the reaction and is facilitated by the environment of cationic polymers, (2) proton abstraction is efficiently accelerated by added cationic surfactant (CTAB), and (3) N-dodecylbenzohydroxamic acid in aqueous CTAB acts as an excellent proton-abstracting reagent. the polymers with high dodecyl group content served, in all cases, as better oxidizing reagents. As a summary of these conclusions, the importance of hydrophobic environments in flavin-mediated oxidation was emphasized.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 3905-3912 |
| ページ数 | 8 |
| ジャーナル | Journal of polymer science. Part A-1, Polymer chemistry |
| 巻 | 17 |
| 発行部数 | 12 |
| 出版物ステータス | 出版済み - 1 1 1979 |
| 外部発表 | Yes |
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All Science Journal Classification (ASJC) codes
- Engineering(all)
これを引用
COENZYME MODELS - 19. OXIDATION OF FUROIN BY A FLAVIN IMMOBILIZED IN CATIONIC POLYELECTROLYTES - A FLAVOENZYME MODEL. / Shinkai, Seiji.
：: Journal of polymer science. Part A-1, Polymer chemistry, 巻 17, 番号 12, 01.01.1979, p. 3905-3912.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - COENZYME MODELS - 19. OXIDATION OF FUROIN BY A FLAVIN IMMOBILIZED IN CATIONIC POLYELECTROLYTES - A FLAVOENZYME MODEL.
AU - Shinkai, Seiji
PY - 1979/1/1
Y1 - 1979/1/1
N2 - In the reported study, the rate constants for the oxidation of furoin by a flavin (vitamin B//2 analog) immobilized in catonic polymers were evaluated under anaerobic conditions, and the influence of reaction environments was discussed in connection with the enzymatic reactivity. It was found that (1) proton abstraction from furoin which forms the carbanionic intermediate is rate determining in the initial stage of the reaction and is facilitated by the environment of cationic polymers, (2) proton abstraction is efficiently accelerated by added cationic surfactant (CTAB), and (3) N-dodecylbenzohydroxamic acid in aqueous CTAB acts as an excellent proton-abstracting reagent. the polymers with high dodecyl group content served, in all cases, as better oxidizing reagents. As a summary of these conclusions, the importance of hydrophobic environments in flavin-mediated oxidation was emphasized.
AB - In the reported study, the rate constants for the oxidation of furoin by a flavin (vitamin B//2 analog) immobilized in catonic polymers were evaluated under anaerobic conditions, and the influence of reaction environments was discussed in connection with the enzymatic reactivity. It was found that (1) proton abstraction from furoin which forms the carbanionic intermediate is rate determining in the initial stage of the reaction and is facilitated by the environment of cationic polymers, (2) proton abstraction is efficiently accelerated by added cationic surfactant (CTAB), and (3) N-dodecylbenzohydroxamic acid in aqueous CTAB acts as an excellent proton-abstracting reagent. the polymers with high dodecyl group content served, in all cases, as better oxidizing reagents. As a summary of these conclusions, the importance of hydrophobic environments in flavin-mediated oxidation was emphasized.
UR - http://www.scopus.com/inward/record.url?scp=0018767801&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018767801&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0018767801
VL - 17
SP - 3905
EP - 3912
JO - Journal of polymer science. Part A-1, Polymer chemistry
JF - Journal of polymer science. Part A-1, Polymer chemistry
SN - 0449-296X
IS - 12
ER -