Colorectal endoscopic submucosal dissection using novel articulating devices

a comparative study in a live porcine model

Yasuharu Okamoto, Ryu Nakadate, Shotaro Nakamura, Jumpei Arata, Susumu Oguri, Moriyama Tomohiko, Motohiro Esaki, tsutomu iwasa, Kenoki Ouchida, Tomohiko Akahoshi, Tetsuo Ikeda, Takanari Kitazono, Makoto Hashizume

研究成果: ジャーナルへの寄稿記事

抄録

Background and aims: Colonic endoscopic submucosal dissection (ESD) is time-consuming and bears a high risk of perforation. The aim of the present study was to compare the safety and efficacy between novel articulating devices and conventional ESD in live porcine colon models. Methods: Thirty ESDs in ten pigs were carried out at three different locations (15, 25, and 35 cm from the anus) by the conventional method (n = 15) and by the new method (n = 15). Procedure times, adverse events (perforation, bleeding), and damage to the muscular layer were recorded, and the ESD time per unit area of the specimens was calculated. Results: The perforation rate using the conventional method was 6.7% (1/15), whereas that using the new method was 0.0%. The number of sites of muscular damage was significantly lower in the new than conventional method (6 vs. 37, respectively; P = 0.024). The mean procedure time was significantly shorter in the new than conventional method (4.6 ± 2.0 vs. 7.0 ± 4.1 min/cm 2 , respectively; P = 0.042). Conclusions: Use of the new ESD method allows for reduced adverse events and a shortened resection time.

元の言語英語
ページ(範囲)651-657
ページ数7
ジャーナルSurgical endoscopy
33
発行部数2
DOI
出版物ステータス出版済み - 2 15 2019

Fingerprint

Swine
Equipment and Supplies
Endoscopic Mucosal Resection
Anal Canal
Colon
Hemorrhage
Safety

All Science Journal Classification (ASJC) codes

  • Surgery

これを引用

Colorectal endoscopic submucosal dissection using novel articulating devices : a comparative study in a live porcine model. / Okamoto, Yasuharu; Nakadate, Ryu; Nakamura, Shotaro; Arata, Jumpei; Oguri, Susumu; Tomohiko, Moriyama; Esaki, Motohiro; iwasa, tsutomu; Ouchida, Kenoki; Akahoshi, Tomohiko; Ikeda, Tetsuo; Kitazono, Takanari; Hashizume, Makoto.

:: Surgical endoscopy, 巻 33, 番号 2, 15.02.2019, p. 651-657.

研究成果: ジャーナルへの寄稿記事

Okamoto, Yasuharu ; Nakadate, Ryu ; Nakamura, Shotaro ; Arata, Jumpei ; Oguri, Susumu ; Tomohiko, Moriyama ; Esaki, Motohiro ; iwasa, tsutomu ; Ouchida, Kenoki ; Akahoshi, Tomohiko ; Ikeda, Tetsuo ; Kitazono, Takanari ; Hashizume, Makoto. / Colorectal endoscopic submucosal dissection using novel articulating devices : a comparative study in a live porcine model. :: Surgical endoscopy. 2019 ; 巻 33, 番号 2. pp. 651-657.
@article{2b2c15ef9932462d8c32b5974765e713,
title = "Colorectal endoscopic submucosal dissection using novel articulating devices: a comparative study in a live porcine model",
abstract = "Background and aims: Colonic endoscopic submucosal dissection (ESD) is time-consuming and bears a high risk of perforation. The aim of the present study was to compare the safety and efficacy between novel articulating devices and conventional ESD in live porcine colon models. Methods: Thirty ESDs in ten pigs were carried out at three different locations (15, 25, and 35 cm from the anus) by the conventional method (n = 15) and by the new method (n = 15). Procedure times, adverse events (perforation, bleeding), and damage to the muscular layer were recorded, and the ESD time per unit area of the specimens was calculated. Results: The perforation rate using the conventional method was 6.7{\%} (1/15), whereas that using the new method was 0.0{\%}. The number of sites of muscular damage was significantly lower in the new than conventional method (6 vs. 37, respectively; P = 0.024). The mean procedure time was significantly shorter in the new than conventional method (4.6 ± 2.0 vs. 7.0 ± 4.1 min/cm 2 , respectively; P = 0.042). Conclusions: Use of the new ESD method allows for reduced adverse events and a shortened resection time.",
author = "Yasuharu Okamoto and Ryu Nakadate and Shotaro Nakamura and Jumpei Arata and Susumu Oguri and Moriyama Tomohiko and Motohiro Esaki and tsutomu iwasa and Kenoki Ouchida and Tomohiko Akahoshi and Tetsuo Ikeda and Takanari Kitazono and Makoto Hashizume",
year = "2019",
month = "2",
day = "15",
doi = "10.1007/s00464-018-6408-5",
language = "English",
volume = "33",
pages = "651--657",
journal = "Surgical Endoscopy",
issn = "0930-2794",
publisher = "Springer New York",
number = "2",

}

TY - JOUR

T1 - Colorectal endoscopic submucosal dissection using novel articulating devices

T2 - a comparative study in a live porcine model

AU - Okamoto, Yasuharu

AU - Nakadate, Ryu

AU - Nakamura, Shotaro

AU - Arata, Jumpei

AU - Oguri, Susumu

AU - Tomohiko, Moriyama

AU - Esaki, Motohiro

AU - iwasa, tsutomu

AU - Ouchida, Kenoki

AU - Akahoshi, Tomohiko

AU - Ikeda, Tetsuo

AU - Kitazono, Takanari

AU - Hashizume, Makoto

PY - 2019/2/15

Y1 - 2019/2/15

N2 - Background and aims: Colonic endoscopic submucosal dissection (ESD) is time-consuming and bears a high risk of perforation. The aim of the present study was to compare the safety and efficacy between novel articulating devices and conventional ESD in live porcine colon models. Methods: Thirty ESDs in ten pigs were carried out at three different locations (15, 25, and 35 cm from the anus) by the conventional method (n = 15) and by the new method (n = 15). Procedure times, adverse events (perforation, bleeding), and damage to the muscular layer were recorded, and the ESD time per unit area of the specimens was calculated. Results: The perforation rate using the conventional method was 6.7% (1/15), whereas that using the new method was 0.0%. The number of sites of muscular damage was significantly lower in the new than conventional method (6 vs. 37, respectively; P = 0.024). The mean procedure time was significantly shorter in the new than conventional method (4.6 ± 2.0 vs. 7.0 ± 4.1 min/cm 2 , respectively; P = 0.042). Conclusions: Use of the new ESD method allows for reduced adverse events and a shortened resection time.

AB - Background and aims: Colonic endoscopic submucosal dissection (ESD) is time-consuming and bears a high risk of perforation. The aim of the present study was to compare the safety and efficacy between novel articulating devices and conventional ESD in live porcine colon models. Methods: Thirty ESDs in ten pigs were carried out at three different locations (15, 25, and 35 cm from the anus) by the conventional method (n = 15) and by the new method (n = 15). Procedure times, adverse events (perforation, bleeding), and damage to the muscular layer were recorded, and the ESD time per unit area of the specimens was calculated. Results: The perforation rate using the conventional method was 6.7% (1/15), whereas that using the new method was 0.0%. The number of sites of muscular damage was significantly lower in the new than conventional method (6 vs. 37, respectively; P = 0.024). The mean procedure time was significantly shorter in the new than conventional method (4.6 ± 2.0 vs. 7.0 ± 4.1 min/cm 2 , respectively; P = 0.042). Conclusions: Use of the new ESD method allows for reduced adverse events and a shortened resection time.

UR - http://www.scopus.com/inward/record.url?scp=85053277559&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85053277559&partnerID=8YFLogxK

U2 - 10.1007/s00464-018-6408-5

DO - 10.1007/s00464-018-6408-5

M3 - Article

VL - 33

SP - 651

EP - 657

JO - Surgical Endoscopy

JF - Surgical Endoscopy

SN - 0930-2794

IS - 2

ER -