TY - JOUR
T1 - Combination cryosurgery with hyperthermia in the management of skin metastasis from breast cancer
T2 - A case report
AU - Hachisuka, Junichi
AU - Doi, Kazuko
AU - Furue, Masutaka
PY - 2012
Y1 - 2012
N2 - INTRODUCTION: Skin metastases may impair the quality of life due to physical appearance, odour, and bleeding. PRESENTATION OF CASE: A 70-year-old woman presented with two enlarging nodules (measuring 12 cm and 3 cm in diameter) consistent with metastatic breast cancer in the left subclavicular area. The larger tumour did not respond to initial cryosurgery. Therefore we added hyperthermia using a disposable body warmer. In addition, the cryosurgery technique was modified to freeze deeper tissue. The entire tumour was covered with dry cotton, to which liquid nitrogen was applied. Twenty weeks later, the tumour became nearly flat and the patient noted improved activity in her daily life. DISCUSSION: Combination treatment with sufficient freezing is important for controlling the tumour, while hyperthermia may accelerate the antitumor effects of cryosurgery. CONCLUTION: This treatment provides an alternative for unresectable breast cancer skin metastases resistant to chemotherapy and radiotherapy.
AB - INTRODUCTION: Skin metastases may impair the quality of life due to physical appearance, odour, and bleeding. PRESENTATION OF CASE: A 70-year-old woman presented with two enlarging nodules (measuring 12 cm and 3 cm in diameter) consistent with metastatic breast cancer in the left subclavicular area. The larger tumour did not respond to initial cryosurgery. Therefore we added hyperthermia using a disposable body warmer. In addition, the cryosurgery technique was modified to freeze deeper tissue. The entire tumour was covered with dry cotton, to which liquid nitrogen was applied. Twenty weeks later, the tumour became nearly flat and the patient noted improved activity in her daily life. DISCUSSION: Combination treatment with sufficient freezing is important for controlling the tumour, while hyperthermia may accelerate the antitumor effects of cryosurgery. CONCLUTION: This treatment provides an alternative for unresectable breast cancer skin metastases resistant to chemotherapy and radiotherapy.
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U2 - 10.1016/j.ijscr.2011.10.016
DO - 10.1016/j.ijscr.2011.10.016
M3 - Article
C2 - 22288049
AN - SCOPUS:84862190168
VL - 3
SP - 68
EP - 69
JO - International Journal of Surgery Case Reports
JF - International Journal of Surgery Case Reports
SN - 2210-2612
IS - 2
ER -
