Common duct carcinoma and obstruction in female hamsters treated with af-nitrosobis(2-oxopropyl)amine and/or cholecystectomy

T. Kamano, A. Katami, J. Tamura, N. Azuma, Y. Mori, T. Makino, K. Mizumoto, Y. Konishi

研究成果: Contribution to journalArticle査読

3 被引用数 (Scopus)

抄録

Detailed histologic observations were performed on the head of the pancreas of hamsters treated with 10 mg/kg body weight /V-nitrosobis(2-oxo-propyl)amine (BOP) once a week for 6 weeks with or without cholecystectomy. Cholecystectomy was performed 5 weeks before starting BOP initiation. The incidence of head cancers was 100% and cholecystectomy did not affect pancreatic carcinogenesis by BOP. Common bile duct dilatation was produced by advanced pancreatic head carcinomas and microadenocarcinomas in common duct. Micro-adenocarcinomas were not macroscopically detected since the tumors were located in the lumen of common duct.

本文言語英語
ページ(範囲)688-693
ページ数6
ジャーナルPancreas
2
6
DOI
出版ステータス出版済み - 11 1987
外部発表はい

All Science Journal Classification (ASJC) codes

  • 内科学
  • 内分泌学、糖尿病および代謝内科学
  • 肝臓学
  • 内分泌学

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