Comparative data on cytophotometric DNA in malignant lesions of the esophagus in the chinese and japanese

Keizo Sugimachi, Yoshihiko Koga, Masaki Mori, Guo Jun Huang, Kan Yang, Ru Gang Zhang

研究成果: Contribution to journalArticle査読

16 被引用数 (Scopus)

抄録

Cell DNA content was microspectrophotometrically determined in tissues of advanced esophageal carcinoma of 50 Chinese and 82 Japanese subjects. DNA distribution patterns were classified into Types I, II, III, and IV, according to the degree of dispersion and the peak value on the DNA histogram. The proportions of high ploidy (Types III and IV) in Chinese and Japanese patients were 68% and 81.7%, respectively. Overall 5‐year survival rates of the Chinese and Japanese were 25.3% and 19.8%, respectively. Five‐year survival rates of patients with Types II, III and IV were 45.7%, 23.8% and 0% in Chinese patients and 57.1%, 16.1%, and 0% in Japanese patients, respectively. Thus, differences in nationality were not related to the prognosis. The incidences of high ploidy group in those with an advanced esophageal carcinoma were high and were associated with a poor prognosis in both races. DNA distribution pattern of esophageal carcinoma reflected the outcome and malignant potential in the Chinese and the Japanese.

本文言語英語
ページ(範囲)1947-1950
ページ数4
ジャーナルCancer
59
11
DOI
出版ステータス出版済み - 6 1 1987
外部発表はい

All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 癌研究

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