抄録
Progression of malignant potential in ovarian cancer was investigated by comparing recurrent tumor with their primary tumor counterparts in terms of p53 and CD44 variant 6 (CD44v6) expression. Forty-three paired primary and recurrent tumors were immunohistochemically evaluated for expression of p53 and CD44v6. A paired analysis revealed that p53 and CD44v6 expression were significantly greater in recurrent tumors than those in the primary counterparts with statistical significance, respectively (P=0.0055 and 0.0071; Wilcoxon signed-rank test). No relationship between these two proteins was found. These results suggested that recurrent ovarian cancer may possibly express a stronger malignant potential in comparison to the primary tumor.
本文言語 | 英語 |
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ページ(範囲) | 97-101 |
ページ数 | 5 |
ジャーナル | Oncology reports |
巻 | 6 |
号 | 1 |
DOI | |
出版ステータス | 出版済み - 1 1 1999 |
All Science Journal Classification (ASJC) codes
- Oncology
- Cancer Research