Comparison of rigid and deformable image registration for nasopharyngeal carcinoma radiotherapy planning with diagnostic position PET/CT

Yudai Kai, Hidetaka Arimura, Ryo Toya, Tetsuo Saito, Tomohiko Matsuyama, Yoshiyuki Fukugawa, Shinya Shiraishi, Yoshinobu Shimohigashi, Masato Maruyama, Natsuo Oya

研究成果: ジャーナルへの寄稿記事

抜粋

Purpose: This observer study aimed to compare rigid image registration (RIR) with deformable image registration (DIR) for diagnostic position (DP) positron emission tomography/computed tomography (PET/CT) images in the delineation of gross tumor volumes (GTVs) in nasopharyngeal carcinoma (NPC) radiotherapy planning. Materials and methods: Four radiation oncologists individually delineated the GTVs, GTVRIR, and GTVDIR, on planning CT (pCT) images registered with DP-PET/CT images using RIR and B-spline-based DIR, respectively. Reference GTVs were independently delineated by all radiation oncologists using radiotherapy position (RP)-PET/CT images. DP- and RP-PET/CT images for 14 patients with NPC were acquired using early and delayed scans, respectively. Dice’s similarity coefficient (DSC), mean distance to agreement, and volume agreement with reference GTVs were compared by considering the interobserver variability in reference contours. Results: The average DSCs for GTVRIR and GTVDIR were 0.77 and 0.77, which were acceptable for GTV delineation. There were no statistically significant differences between GTVRIR and GTVDIR in all evaluation indexes (p > 0.05). Furthermore, the correlation between neck flexion angle differences and GTV accuracy was not statistically significant (p > 0.05). Conclusion: RIR was a feasible choice compared with the B-spline-based DIR in GTV delineation for NPC under variations of neck flexion angle.

元の言語英語
ページ(範囲)256-264
ページ数9
ジャーナルJapanese Journal of Radiology
38
発行部数3
DOI
出版物ステータス出版済み - 3 1 2020

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

フィンガープリント Comparison of rigid and deformable image registration for nasopharyngeal carcinoma radiotherapy planning with diagnostic position PET/CT' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用