Concurrent benzodiazepine use in older adults treated with antidepressants in Asia

Xiao Mei Zhong, Fei Wang, Qinge Zhang, Gabor S. Ungvari, Chee H. Ng, Helen F.K. Chiu, Tian Mei Si, Kang Sim, Ajit Avasthi, Sandeep Grover, Mian Yoon Chong, Kok Yoon Chee, Shigenobu Kanba, Min Soo Lee, Shu Yu Yang, Pichet Udomratn, Roy A. Kallivayalil, Andi J. Tanra, Margarita M. Maramis, Winston W. ShenNorman Sartorius, Rathi Mahendran, Chay Hoon Tan, Naotaka Shinfuku, Yu Tao Xiang

研究成果: ジャーナルへの寄稿学術誌査読

6 被引用数 (Scopus)

抄録

Background: Little is known about the combined use of benzodiazepines and antidepressants in older psychiatric patients. This study examined the prescription pattern of concurrent benzodiazepines in older adults treated with antidepressants in Asia, and explored its demographic and clinical correlates.Methods: The data of 955 older adults with any type of psychiatric disorders were extracted from the database of the Research on Asian Psychotropic Prescription Patterns for Antidepressants (REAP-AD) project. Demographic and clinical characteristics were recorded using a standardized protocol and data collection procedure. Both univariate and multiple logistic regression analyses were performed.Results: The proportion of benzodiazepine and antidepressant combination in this cohort was 44.3%. Multiple logistic regression analysis revealed that higher doses of antidepressants, younger age (<65 years), inpatients, public hospital, major comorbid medical conditions, antidepressant types, and country/territory were significantly associated with more frequent co-prescription of benzodiazepines and antidepressants.Conclusions: Nearly, half of the older adults treated with antidepressants in Asia are prescribed concurrent benzodiazepines. Given the potentially adverse effects of benzodiazepines, the rationale of benzodiazepines and antidepressants co-prescription needs to be revisited.

本文言語英語
ページ(範囲)685-691
ページ数7
ジャーナルInternational Psychogeriatrics
31
5
DOI
出版ステータス出版済み - 5月 1 2019
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 臨床心理学
  • 老年学
  • 老年医学
  • 精神医学および精神衛生

フィンガープリント

「Concurrent benzodiazepine use in older adults treated with antidepressants in Asia」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル