TY - JOUR
T1 - Condensed catechins and their potential health-benefits
AU - Matsui, Toshiro
PY - 2015/10/15
Y1 - 2015/10/15
N2 - Condensed catechins are commonly present in fermented tea, and are produced by the oxidation of monomeric catechins. Due to their auto-oxidation, catechins have diverse structural features, including different binding modes and degrees of polymerization. Because of their structural complexity, their physiological functions and possible health-benefits have not yet been fully investigated. This review focuses on the physiological potentials of dimeric and trimeric catechins in the intestine (regulation of absorption across the intestinal membrane), blood vessels (vasorelaxation in vessel regulation), and muscle organs (promotion of glucose uptake resulting in an anti-diabetic effect). Furthermore, the roles of non-absorbable theaflavins (dimeric catechins), absorbable theasinensins (dimeric catechins), and absorbable procyanidins (dimeric and trimeric catechins) on target organs are discussed.
AB - Condensed catechins are commonly present in fermented tea, and are produced by the oxidation of monomeric catechins. Due to their auto-oxidation, catechins have diverse structural features, including different binding modes and degrees of polymerization. Because of their structural complexity, their physiological functions and possible health-benefits have not yet been fully investigated. This review focuses on the physiological potentials of dimeric and trimeric catechins in the intestine (regulation of absorption across the intestinal membrane), blood vessels (vasorelaxation in vessel regulation), and muscle organs (promotion of glucose uptake resulting in an anti-diabetic effect). Furthermore, the roles of non-absorbable theaflavins (dimeric catechins), absorbable theasinensins (dimeric catechins), and absorbable procyanidins (dimeric and trimeric catechins) on target organs are discussed.
UR - http://www.scopus.com/inward/record.url?scp=84943339711&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84943339711&partnerID=8YFLogxK
U2 - 10.1016/j.ejphar.2015.09.017
DO - 10.1016/j.ejphar.2015.09.017
M3 - Review article
C2 - 26386288
AN - SCOPUS:84943339711
VL - 765
SP - 495
EP - 502
JO - European Journal of Pharmacology
JF - European Journal of Pharmacology
SN - 0014-2999
ER -