Constituents of holothuroidea, 8([≠]). - Structure of neuritogenic active ganglioside from the sea cucumber Stichopus japonicus

Masafumi Kaneko, Fumiaki Kisa, Koji Yamada, Tomofumi Miyamoto, Ryuichi Higuchi

研究成果: ジャーナルへの寄稿記事

28 引用 (Scopus)

抄録

A ganglioside molecular species SJG-1 has been obtained from the n- hexane soluble lipid fraction of the chloroform/ methanol extract of the sea cucumber Stichopus japonicus. On the basis of chemical and spectroscopic evidence, the structure of SJG-1 has been determined. SJG-1 possesses an N- glycolylneuraminic acid (sialic acid), nonhydroxy fatty acids and phytosphingosine-type long-chain bases as major ceramide components. The ganglioside SJG-1 exhibits neuritogenic activity toward the rat pheochromocytoma cell line PC12 cells in the presence of NGF.

元の言語英語
ページ(範囲)3171-3174
ページ数4
ジャーナルEuropean Journal of Organic Chemistry
発行部数11
出版物ステータス出版済み - 11 1 1999

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phytosphingosine
Gangliosides
acids
Ceramides
N-Acetylneuraminic Acid
Nerve Growth Factor
fatty acids
Chloroform
chloroform
cultured cells
rats
Methanol
lipids
Rats
Fatty Acids
methyl alcohol
Cells
Lipids
cells
n-hexane

All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Organic Chemistry

これを引用

Constituents of holothuroidea, 8([≠]). - Structure of neuritogenic active ganglioside from the sea cucumber Stichopus japonicus. / Kaneko, Masafumi; Kisa, Fumiaki; Yamada, Koji; Miyamoto, Tomofumi; Higuchi, Ryuichi.

:: European Journal of Organic Chemistry, 番号 11, 01.11.1999, p. 3171-3174.

研究成果: ジャーナルへの寄稿記事

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AU - Higuchi, Ryuichi

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