Construction of a blood-compatible interface based on surface segregation in a polymer blend

Toyoaki Hirata, Hisao Matsuno, Daisuke Kawaguchi, Norifumi L. Yamada, Masaru Tanaka, Keiji Tanaka

研究成果: Contribution to journalArticle査読

10 被引用数 (Scopus)

抄録

The technique of surface segregation was applied to prepare a bio-inert polymer interface. A small amount, 10 wt%, of poly(2-methoxyethyl acrylate) (PMEA), which exhibits excellent bio-inertness properties, fed into a matrix polymer was able to suppress platelet adhesion sufficiently to be of practical use. PMEA was effective because it was preferentially segregated at the outermost region of the polymer blend. Combining interfacial-sensitive analyses such as the air bubble contact angle and neutron reflectivity measurements and sum-frequency generation spectroscopy with the platelet adhesion test gives a better understanding of how the bio-inert property is expressed at the water interface.

本文言語英語
ページ(範囲)219-224
ページ数6
ジャーナルpolymer
78
DOI
出版ステータス出版済み - 11 5 2015

All Science Journal Classification (ASJC) codes

  • 有機化学
  • ポリマーおよびプラスチック
  • 材料化学

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