Construction of multimodal 3D model of pancreatic cancer tumor

Yushi Goto, Mauricio Kugler, Tatsuya Yokota, Chika Iwamoto, Kenoki Ouchida, Makoto Hashizume, Hidekata Hontani

研究成果: 著書/レポートタイプへの貢献会議での発言

抄録

Histopathological imaging and Magnetic Resonance (MR) are two equally important yet very distinct modalities of medical imaging. The high resolution of the first and the non-invasiveness of the later provide complementary information for medical diagnosis and research. Due to their largely different resolutions, the registration between 3D images of these two modalities is challenging. The objective of this paper is to create a multimodal 3D model of pancreatic cancer tumor by performing the registration of a reconstructed 3D pathological image and an MR image from a KPC mouse. The tumor portions were manually segmented and the 3D pathological image was reconstructed using landmark-based non-linear registration. The process starts by registering the outline of the images using the LDDMM non-linear registration method to match the binary labels of the tumor regions. Next, a non-linear B-spline deformation method based on mutual information maximization is used to register the internal structures of the images. Experimental results show that the overall shape of the tumor and its internal necrosis portion could be correctly registered, although the quality of the manual segmentations affects the accuracy of the registration.

元の言語英語
ホスト出版物のタイトルInternational Forum on Medical Imaging in Asia 2019
編集者Feng Lin, Jong Hyo Kim, Hiroshi Fujita
出版者SPIE
ISBN(電子版)9781510627758
DOI
出版物ステータス出版済み - 1 1 2019
イベントInternational Forum on Medical Imaging in Asia 2019 - Singapore, シンガポール
継続期間: 1 7 20191 9 2019

出版物シリーズ

名前Proceedings of SPIE - The International Society for Optical Engineering
11050
ISSN(印刷物)0277-786X
ISSN(電子版)1996-756X

会議

会議International Forum on Medical Imaging in Asia 2019
シンガポール
Singapore
期間1/7/191/9/19

Fingerprint

3D Model
Registration
Tumors
Tumor
Cancer
tumors
cancer
3D Image
Magnetic resonance
Modality
magnetic resonance
Medical imaging
Internal
Necrosis
Magnetic Resonance Image
Splines
Magnetic Resonance
Medical Imaging
Labels
Landmarks

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

これを引用

Goto, Y., Kugler, M., Yokota, T., Iwamoto, C., Ouchida, K., Hashizume, M., & Hontani, H. (2019). Construction of multimodal 3D model of pancreatic cancer tumor. : F. Lin, J. H. Kim, & H. Fujita (版), International Forum on Medical Imaging in Asia 2019 [110501H] (Proceedings of SPIE - The International Society for Optical Engineering; 巻数 11050). SPIE. https://doi.org/10.1117/12.2521394

Construction of multimodal 3D model of pancreatic cancer tumor. / Goto, Yushi; Kugler, Mauricio; Yokota, Tatsuya; Iwamoto, Chika; Ouchida, Kenoki; Hashizume, Makoto; Hontani, Hidekata.

International Forum on Medical Imaging in Asia 2019. 版 / Feng Lin; Jong Hyo Kim; Hiroshi Fujita. SPIE, 2019. 110501H (Proceedings of SPIE - The International Society for Optical Engineering; 巻 11050).

研究成果: 著書/レポートタイプへの貢献会議での発言

Goto, Y, Kugler, M, Yokota, T, Iwamoto, C, Ouchida, K, Hashizume, M & Hontani, H 2019, Construction of multimodal 3D model of pancreatic cancer tumor. : F Lin, JH Kim & H Fujita (版), International Forum on Medical Imaging in Asia 2019., 110501H, Proceedings of SPIE - The International Society for Optical Engineering, 巻. 11050, SPIE, International Forum on Medical Imaging in Asia 2019, Singapore, シンガポール, 1/7/19. https://doi.org/10.1117/12.2521394
Goto Y, Kugler M, Yokota T, Iwamoto C, Ouchida K, Hashizume M その他. Construction of multimodal 3D model of pancreatic cancer tumor. : Lin F, Kim JH, Fujita H, 編集者, International Forum on Medical Imaging in Asia 2019. SPIE. 2019. 110501H. (Proceedings of SPIE - The International Society for Optical Engineering). https://doi.org/10.1117/12.2521394
Goto, Yushi ; Kugler, Mauricio ; Yokota, Tatsuya ; Iwamoto, Chika ; Ouchida, Kenoki ; Hashizume, Makoto ; Hontani, Hidekata. / Construction of multimodal 3D model of pancreatic cancer tumor. International Forum on Medical Imaging in Asia 2019. 編集者 / Feng Lin ; Jong Hyo Kim ; Hiroshi Fujita. SPIE, 2019. (Proceedings of SPIE - The International Society for Optical Engineering).
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