Continuous ictal discharges with high frequency oscillations confined to the non-sclerotic hippocampus in an epileptic patient with radiation-induced cavernoma in the lateral temporal lobe

Nobutaka Mukae, Takato Morioka, Michiko Torio, Ayumi Sakata, Satoshi O. Suzuki, Koji Iihara

研究成果: ジャーナルへの寄稿記事


Background: Intraoperative electrocorticography (iECoG) recording is recommended for treating cavernoma related epilepsy. However, “interictal” paroxysmal activities are generally recordable but are not always identical to the epileptogenic zone. Case description: We surgically treated a 15-year-old girl with drug-resistant epilepsy associated with radiation-induced cavernoma in the right lateral temporal lobe. iECoG revealed paroxysmal activities in the cortex around the cavernoma. Additionally, continuous subclinical “ictal” discharges with high-frequency oscillations (HFO), confined to the histologically non-sclerotic hippocampus, were recorded. Following additional hippocampectomy, a good seizure outcome was obtained. Conclusion: iECoG and HFO analysis revealed high epileptogenicity in the non-sclerotic hippocampus of this patient.

ジャーナルEpilepsy and Behavior Case Reports
出版物ステータス出版済み - 1 1 2019


All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience