Contribution of maternal mRNA for maintenance of Ca2+-dependent reaggregating activity in dissociated cells of Xenopus laevis embryos

K. Shiokawa, K. Tashiro, T. Oka, K. Yamana

研究成果: Contribution to journalArticle査読

17 被引用数 (Scopus)

抄録

Dissociated Xenopus laevis blastula cells, where reaggregation was inhibited in Ca2+-free medium, reaggregated immediately after the addition of Ca2+. This reaggregation was not inhibited by cordycepin or actinomycin D treatment during culture, although cycloheximide and puromycin were inhibitory. The reaggregation was not inhibited even when fertilized eggs were microinjected with cordycepin and their RNA synthesis was continuously inhibited through cleavage to blastula stages. In neurula cells, cordycepin treatment induced significant reduction in sizes of aggregates formed. These results suggest that the Ca2+-dependent reaggregating activity of blastula cells is maintained by the translation of maternal, rather than newly synthesized, mRNA.

本文言語英語
ページ(範囲)247-255
ページ数9
ジャーナルCell Differentiation
13
3
DOI
出版ステータス出版済み - 11 1983

All Science Journal Classification (ASJC) codes

  • 発生生物学

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