In this study, we propose a method to control the wheelchair by eye movement using Electroencephalography (EEG). Firstly, we collect EEG signal by five types of eye movement: Blink, Double blink, look at Right, look at Left and Relax. These movements correspond to five directions of wheelchair motion: Go forward, Go backward, Turn right, Turn left and Stop. After that, the offline EEG signal is analyzed using MATLAB to find out the classified threshold of the signal amplitude in Alpha band and Delta band. Finally, an effective algorithm is built allowing us to identify the type of eye movement and control the external device—the powered wheelchair. As the result, the average accuracy for five motion directions (Go forward, Go backward, Turn right, Turn left and Stop) are 92.333, 93, 81.667, 86.667 and 83% respectively. With this study, we expect it can give people the help they need and be applied to many fields in the near future.