Convergent synthesis and biological activity of the WXYZA′B′ C′ ring system of maitotoxin

Tohru Oishi, Futoshi Hasegawa, Kohei Torikai, Keiichi Konoki, Nobuaki Matsumori, Michio Murata

研究成果: ジャーナルへの寄稿記事

28 引用 (Scopus)

抄録

(Chemical Equation Presented) The WXYZA′B′C′ ring system (1) of maitotoxin (MTX) was synthesized in a convergent manner via successive coupling of the W, Z, and C′ ring fragments through construction of the XY and A′B′ ring systems. The synthetic segment 1 blocked the hemolytic activity elicited by MTX.

元の言語英語
ページ(範囲)3599-3602
ページ数4
ジャーナルOrganic Letters
10
発行部数16
DOI
出版物ステータス出版済み - 12 1 2008
外部発表Yes

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activity (biology)
Bioactivity
rings
synthesis
fragments
maitotoxin

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

これを引用

Convergent synthesis and biological activity of the WXYZA′B′ C′ ring system of maitotoxin. / Oishi, Tohru; Hasegawa, Futoshi; Torikai, Kohei; Konoki, Keiichi; Matsumori, Nobuaki; Murata, Michio.

:: Organic Letters, 巻 10, 番号 16, 01.12.2008, p. 3599-3602.

研究成果: ジャーナルへの寄稿記事

Oishi, Tohru ; Hasegawa, Futoshi ; Torikai, Kohei ; Konoki, Keiichi ; Matsumori, Nobuaki ; Murata, Michio. / Convergent synthesis and biological activity of the WXYZA′B′ C′ ring system of maitotoxin. :: Organic Letters. 2008 ; 巻 10, 番号 16. pp. 3599-3602.
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