Cross-talks between transcription and post-transcriptional events within a 'mRNA factory'

Masatoshi Hagiwara, Takayuki Nojima

研究成果: Contribution to journalShort survey査読

20 被引用数 (Scopus)

抄録

Eukaryotic gene expression is controlled in multi steps. Pre-messenger RNAs (pre-mRNAs) transcribed by RNA polymerase II (RNAPII) are capped at 5′ end, spliced to remove introns and polyadenylated at 3′ end. These processes are followed by other post-transcriptional steps that include mRNA export, translation and mRNA degradation. Recent studies have shown that individual events occurring during eukaryotic gene expression are coupled together under more elaborate regulatory controls. In this review, the molecular and functional cross-talks between transcription and the post-transcriptional events are overviewed.

本文言語英語
ページ(範囲)11-15
ページ数5
ジャーナルJournal of biochemistry
142
1
DOI
出版ステータス出版済み - 7 2007
外部発表はい

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology

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