Cryoablation for Secondary Renal Cell Carcinoma After Surgical Nephrectomy

Yasuhiro Ushijima, Yoshiki Asayama, Akihiro Nishie, Yukihisa Takayama, yuichiro kubo, Keisuke Ishimatsu, Kousei Ishigami

研究成果: ジャーナルへの寄稿学術誌査読

抄録

Purpose: To retrospectively evaluate the clinical outcomes of cryoablation for secondary renal cell carcinoma for patients with a history of nephrectomy for initial renal cell carcinoma. Materials and Methods: Thirty patients with 40 renal tumors who had undergone a nephrectomy for initial renal cell carcinoma and cryoablation for renal cell carcinoma as a secondary treatment during the period from April 2014 to December 2018 at a single center institution were enrolled. The patients' overall survival, local control, relapse-free survival, change of renal function, and complications were evaluated. The clinical factors of relapse-free survival were also evaluated. Results: The 5 year overall survival rate was 94.5%, the 5 year local control rate was 89.3%, and the 5 year relapse-free survival rate (RFSR) was 56.3%. There was an average reduction in renal function of 8.5% after 1 year, and > grade 3 complications occurred in only one case. The RFSR in the patients whose initial stage was T3 was 0%, significantly lower than the 70.4% RFSR in the patients whose initial stage was T1 or T2. Conclusion: Cryoablation for secondary renal cell carcinoma after nephrectomy was safe and provided good local control with preserved renal function. However, the indications for cryoablation should be carefully considered for patients with T3-stage initial renal cell carcinoma, because of the high risk of relapse. Level of evidence: III

本文言語英語
ページ(範囲)414-420
ページ数7
ジャーナルCardioVascular and Interventional Radiology
44
3
DOI
出版ステータス出版済み - 3月 2021

!!!All Science Journal Classification (ASJC) codes

  • 放射線学、核医学およびイメージング
  • 循環器および心血管医学

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