Crystallization of Human Erythrocyte Band 3, the anion exchanger, at the International Space Station “KIBO”

Hinako Hatae, Koji Inaka, Ryo Okamura, Naoki Furubayashi, Masayuki Kamo, Takuya Kobayashi, Yoshito Abe, So Iwata, Naotaka Hamasaki

研究成果: ジャーナルへの寄稿学術誌査読

6 被引用数 (Scopus)

抄録

Band 3 mediates the Cl and HCO3 exchange across the red blood cell membrane and plays a pivotal role for delivering oxygen appropriately to metabolically active tissues. For understanding molecular mechanisms, it is essential to know the structure and function relationship. In terrestrial environments, however, nobody could make good quality crystals of Band 3 for the X-ray crystallographic study. In this study, we purified the transmembrane domain of Band 3 from human red blood cells and crystallized the purified Band 3 without the Fab fragment at the International Space Station “KIBO” under microgravity environments.

本文言語英語
ページ(範囲)91-93
ページ数3
ジャーナルAnalytical Biochemistry
559
DOI
出版ステータス出版済み - 10月 15 2018

!!!All Science Journal Classification (ASJC) codes

  • 生物理学
  • 生化学
  • 分子生物学
  • 細胞生物学

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