C1-symmetric Rh/Phebox-catalyzed asymmetric alkynylation of α-ketoesters

Takashi Ohshima, Takahito Kawabata, Yosuke Takeuchi, Takahiro Kakinuma, Takanori Iwasaki, Takayuki Yonezawa, Hajime Murakami, Hisao Nishiyama, Kazushi Mashima

研究成果: ジャーナルへの寄稿記事

80 引用 (Scopus)

抜粋

Thinking outside the box: A newly developed C1-symmetric Rh/Phebox complex efficiently catalyzed the asymmetric alkynylation of α-ketoester 1 with various aryl and alkyl substituted terminal alkynes to provide the corresponding chiral tertiary propargylic alcohols with up to 99 % ee (see scheme; TMS=trimethylsilyl).

元の言語英語
ページ(範囲)6296-6300
ページ数5
ジャーナルAngewandte Chemie - International Edition
50
発行部数28
DOI
出版物ステータス出版済み - 7 4 2011

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

これを引用

Ohshima, T., Kawabata, T., Takeuchi, Y., Kakinuma, T., Iwasaki, T., Yonezawa, T., ... Mashima, K. (2011). C1-symmetric Rh/Phebox-catalyzed asymmetric alkynylation of α-ketoesters. Angewandte Chemie - International Edition, 50(28), 6296-6300. https://doi.org/10.1002/anie.201100252