Current clinical features in diagnosis and treatment for immaturity of ganglia in Japan: analysis from 10-year nationwide survey

Satoshi Ieiri, Kina Miyoshi, Kouji Nagata, Junko Miyata, Kennichi Kohashi, Yoshinao Oda, Tomoaki Taguchi

研究成果: ジャーナルへの寄稿記事

抄録

Background: To identify the current clinical features in diagnosis and treatment for immaturity of ganglia (IG) in Japan, we retrospectively analyzed data for patients with IG from the nationwide surveys in Japan. This survey was performed by Japanese Study Group of allied disorders of Hirschsprung’s disease (ADHD). Methods: In primary research, data on totally 355 cases of ADHD were collected for 10 years (2001–2010). Fifteen patients were IG. All IG patients were confirmed by pathological examination. In secondary research, detail questionnaires were sent and collected. Results: Male/female ratio was 9/6 and mean birth weight was 2474 g. All cases (100 %) were onset in neonatal period. Primary symptoms were abdominal distention (86.7 %), vomiting (53.3 %), and late egestion of meconium (26.7 %). An abnormal distention of intestine was recognized in 86.7 % on X-ray, and microcolon was recognized in 58.3 % on contrast enema. Caliber change was recognized in 58.3 % on laparotomy. An enterostomy was made in 13 patients (86.7 %), and an ileostomy was made in 69.2 %. Pathological diagnosis was performed in 100 %. Enterostomy was closed in 100 %. Conclusions: Totally, 15 definitive cases of IG in 10 years were collected and analyzed. All cases were onset in the neonatal period and almost all underwent enterostomy, but no mortalities occurred.

元の言語英語
ページ(範囲)949-954
ページ数6
ジャーナルPediatric surgery international
31
発行部数10
DOI
出版物ステータス出版済み - 10 22 2015

Fingerprint

Ganglia
Enterostomy
Japan
Hirschsprung Disease
Therapeutics
Meconium
Ileostomy
Enema
Research
Birth Weight
Laparotomy
Intestines
Vomiting
X-Rays
Surveys and Questionnaires
Mortality

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Surgery

これを引用

@article{b50c32978df142cc8cf4e2e46f533524,
title = "Current clinical features in diagnosis and treatment for immaturity of ganglia in Japan: analysis from 10-year nationwide survey",
abstract = "Background: To identify the current clinical features in diagnosis and treatment for immaturity of ganglia (IG) in Japan, we retrospectively analyzed data for patients with IG from the nationwide surveys in Japan. This survey was performed by Japanese Study Group of allied disorders of Hirschsprung’s disease (ADHD). Methods: In primary research, data on totally 355 cases of ADHD were collected for 10 years (2001–2010). Fifteen patients were IG. All IG patients were confirmed by pathological examination. In secondary research, detail questionnaires were sent and collected. Results: Male/female ratio was 9/6 and mean birth weight was 2474 g. All cases (100 {\%}) were onset in neonatal period. Primary symptoms were abdominal distention (86.7 {\%}), vomiting (53.3 {\%}), and late egestion of meconium (26.7 {\%}). An abnormal distention of intestine was recognized in 86.7 {\%} on X-ray, and microcolon was recognized in 58.3 {\%} on contrast enema. Caliber change was recognized in 58.3 {\%} on laparotomy. An enterostomy was made in 13 patients (86.7 {\%}), and an ileostomy was made in 69.2 {\%}. Pathological diagnosis was performed in 100 {\%}. Enterostomy was closed in 100 {\%}. Conclusions: Totally, 15 definitive cases of IG in 10 years were collected and analyzed. All cases were onset in the neonatal period and almost all underwent enterostomy, but no mortalities occurred.",
author = "Satoshi Ieiri and Kina Miyoshi and Kouji Nagata and Junko Miyata and Kennichi Kohashi and Yoshinao Oda and Tomoaki Taguchi",
year = "2015",
month = "10",
day = "22",
doi = "10.1007/s00383-015-3774-0",
language = "English",
volume = "31",
pages = "949--954",
journal = "Pediatric Surgery International",
issn = "0179-0358",
publisher = "Springer Verlag",
number = "10",

}

TY - JOUR

T1 - Current clinical features in diagnosis and treatment for immaturity of ganglia in Japan

T2 - analysis from 10-year nationwide survey

AU - Ieiri, Satoshi

AU - Miyoshi, Kina

AU - Nagata, Kouji

AU - Miyata, Junko

AU - Kohashi, Kennichi

AU - Oda, Yoshinao

AU - Taguchi, Tomoaki

PY - 2015/10/22

Y1 - 2015/10/22

N2 - Background: To identify the current clinical features in diagnosis and treatment for immaturity of ganglia (IG) in Japan, we retrospectively analyzed data for patients with IG from the nationwide surveys in Japan. This survey was performed by Japanese Study Group of allied disorders of Hirschsprung’s disease (ADHD). Methods: In primary research, data on totally 355 cases of ADHD were collected for 10 years (2001–2010). Fifteen patients were IG. All IG patients were confirmed by pathological examination. In secondary research, detail questionnaires were sent and collected. Results: Male/female ratio was 9/6 and mean birth weight was 2474 g. All cases (100 %) were onset in neonatal period. Primary symptoms were abdominal distention (86.7 %), vomiting (53.3 %), and late egestion of meconium (26.7 %). An abnormal distention of intestine was recognized in 86.7 % on X-ray, and microcolon was recognized in 58.3 % on contrast enema. Caliber change was recognized in 58.3 % on laparotomy. An enterostomy was made in 13 patients (86.7 %), and an ileostomy was made in 69.2 %. Pathological diagnosis was performed in 100 %. Enterostomy was closed in 100 %. Conclusions: Totally, 15 definitive cases of IG in 10 years were collected and analyzed. All cases were onset in the neonatal period and almost all underwent enterostomy, but no mortalities occurred.

AB - Background: To identify the current clinical features in diagnosis and treatment for immaturity of ganglia (IG) in Japan, we retrospectively analyzed data for patients with IG from the nationwide surveys in Japan. This survey was performed by Japanese Study Group of allied disorders of Hirschsprung’s disease (ADHD). Methods: In primary research, data on totally 355 cases of ADHD were collected for 10 years (2001–2010). Fifteen patients were IG. All IG patients were confirmed by pathological examination. In secondary research, detail questionnaires were sent and collected. Results: Male/female ratio was 9/6 and mean birth weight was 2474 g. All cases (100 %) were onset in neonatal period. Primary symptoms were abdominal distention (86.7 %), vomiting (53.3 %), and late egestion of meconium (26.7 %). An abnormal distention of intestine was recognized in 86.7 % on X-ray, and microcolon was recognized in 58.3 % on contrast enema. Caliber change was recognized in 58.3 % on laparotomy. An enterostomy was made in 13 patients (86.7 %), and an ileostomy was made in 69.2 %. Pathological diagnosis was performed in 100 %. Enterostomy was closed in 100 %. Conclusions: Totally, 15 definitive cases of IG in 10 years were collected and analyzed. All cases were onset in the neonatal period and almost all underwent enterostomy, but no mortalities occurred.

UR - http://www.scopus.com/inward/record.url?scp=84941935425&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84941935425&partnerID=8YFLogxK

U2 - 10.1007/s00383-015-3774-0

DO - 10.1007/s00383-015-3774-0

M3 - Article

C2 - 26296508

AN - SCOPUS:84941935425

VL - 31

SP - 949

EP - 954

JO - Pediatric Surgery International

JF - Pediatric Surgery International

SN - 0179-0358

IS - 10

ER -