Cyanobacterial production of 1,3-propanediol directly from carbon dioxide using a synthetic metabolic pathway

Yasutaka Hirokawa, Yuki Maki, Tsuneyuki Tatsuke, Taizo Hanai

研究成果: Contribution to journalArticle査読

40 被引用数 (Scopus)

抄録

Production of chemicals directly from carbon dioxide using light energy is an attractive option for a sustainable future. The 1,3-propanediol (1,3-PDO) production directly from carbon dioxide was achieved by engineered Synechococcus elongatus PCC 7942 with a synthetic metabolic pathway. Glycerol dehydratase catalyzing the conversion of glycerol to 3-hydroxypropionaldehyde in a coenzyme B12-dependent manner worked in S. elongatus PCC 7942 without addition of vitamin B12, suggesting that the intrinsic pseudovitamin B12 served as a substitute of coenzyme B12. The highest titers of 1,3-PDO (3.79±0.23mM; 288±17.7mg/L) and glycerol (12.62±1.55mM; 1.16±0.14g/L), precursor of 1,3-PDO, were reached after 14 days of culture under optimized conditions in this study.

本文言語英語
ページ(範囲)97-103
ページ数7
ジャーナルMetabolic Engineering
34
DOI
出版ステータス出版済み - 3 1 2016

All Science Journal Classification (ASJC) codes

  • バイオテクノロジー
  • バイオエンジニアリング
  • 応用微生物学とバイオテクノロジー

フィンガープリント

「Cyanobacterial production of 1,3-propanediol directly from carbon dioxide using a synthetic metabolic pathway」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル