Cyclosproine A inhibits accessory cell and antigen-presenting cell functions of epidermal Langerhans cells

M. Furue, S. I. Katz

研究成果: ジャーナルへの寄稿記事

21 引用 (Scopus)

抄録

Cyclosprorine A (CsA) inhibits immune responses mainly by impairing the production of interleukin 2 (IL 2) and other lymphokines by activated T cells. In addition, functional subsets of B cells and antigen-presenting cells are sensitive to the suppressive effects of CsA. Because epidermal Langerhans cells (LC) are potent antigen-presenting and accessory cells, and because topically applied CsA has been shwon to inhibit contact dermatitis in vivo, we have investigated the in vitro and in vivo effects of CsA on LC functions. Detailed results of the effects of in vitro treatment with CsA of LC are reported elsewhere.

元の言語英語
ページ(範囲)87-91
ページ数5
ジャーナルTransplantation Proceedings
20
発行部数2 SUPPL. 2
出版物ステータス出版済み - 1 1 1988

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Langerhans Cells
Antigen-Presenting Cells
B-Lymphocyte Subsets
Lymphokines
Contact Dermatitis
Interleukin-2
T-Lymphocytes
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Surgery
  • Transplantation

これを引用

Cyclosproine A inhibits accessory cell and antigen-presenting cell functions of epidermal Langerhans cells. / Furue, M.; Katz, S. I.

:: Transplantation Proceedings, 巻 20, 番号 2 SUPPL. 2, 01.01.1988, p. 87-91.

研究成果: ジャーナルへの寄稿記事

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