抄録
Cyclosprorine A (CsA) inhibits immune responses mainly by impairing the production of interleukin 2 (IL 2) and other lymphokines by activated T cells. In addition, functional subsets of B cells and antigen-presenting cells are sensitive to the suppressive effects of CsA. Because epidermal Langerhans cells (LC) are potent antigen-presenting and accessory cells, and because topically applied CsA has been shwon to inhibit contact dermatitis in vivo, we have investigated the in vitro and in vivo effects of CsA on LC functions. Detailed results of the effects of in vitro treatment with CsA of LC are reported elsewhere.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 87-91 |
| ページ数 | 5 |
| ジャーナル | Transplantation Proceedings |
| 巻 | 20 |
| 発行部数 | 2 SUPPL. 2 |
| 出版物ステータス | 出版済み - 1 1 1988 |
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All Science Journal Classification (ASJC) codes
- Surgery
- Transplantation
これを引用
Cyclosproine A inhibits accessory cell and antigen-presenting cell functions of epidermal Langerhans cells. / Furue, M.; Katz, S. I.
：: Transplantation Proceedings, 巻 20, 番号 2 SUPPL. 2, 01.01.1988, p. 87-91.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - Cyclosproine A inhibits accessory cell and antigen-presenting cell functions of epidermal Langerhans cells
AU - Furue, M.
AU - Katz, S. I.
PY - 1988/1/1
Y1 - 1988/1/1
N2 - Cyclosprorine A (CsA) inhibits immune responses mainly by impairing the production of interleukin 2 (IL 2) and other lymphokines by activated T cells. In addition, functional subsets of B cells and antigen-presenting cells are sensitive to the suppressive effects of CsA. Because epidermal Langerhans cells (LC) are potent antigen-presenting and accessory cells, and because topically applied CsA has been shwon to inhibit contact dermatitis in vivo, we have investigated the in vitro and in vivo effects of CsA on LC functions. Detailed results of the effects of in vitro treatment with CsA of LC are reported elsewhere.
AB - Cyclosprorine A (CsA) inhibits immune responses mainly by impairing the production of interleukin 2 (IL 2) and other lymphokines by activated T cells. In addition, functional subsets of B cells and antigen-presenting cells are sensitive to the suppressive effects of CsA. Because epidermal Langerhans cells (LC) are potent antigen-presenting and accessory cells, and because topically applied CsA has been shwon to inhibit contact dermatitis in vivo, we have investigated the in vitro and in vivo effects of CsA on LC functions. Detailed results of the effects of in vitro treatment with CsA of LC are reported elsewhere.
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UR - http://www.scopus.com/inward/citedby.url?scp=0023818364&partnerID=8YFLogxK
M3 - Article
C2 - 3259044
AN - SCOPUS:0023818364
VL - 20
SP - 87
EP - 91
JO - Transplantation Proceedings
JF - Transplantation Proceedings
SN - 0041-1345
IS - 2 SUPPL. 2
ER -