CYLD in Ubiquitin Signaling and Tumor Pathogenesis

Fumiyo Ikeda, Ivan Dikic

研究成果: Contribution to journalShort survey

23 引用 (Scopus)

抜粋

Absence of CYLD, which encodes a deubiquitinating enzyme, causes an inherited disease characterized by benign skin tumors. In this issue of Cell, Massoumi et al. (2006) show that CYLD deubiquitinates the coactivator Bcl-3, thereby preventing its translocation into the nucleus, where it normally interacts with NF-κB and activates transcription of proliferation genes in response to growth signals.

元の言語英語
ページ(範囲)643-645
ページ数3
ジャーナルCell
125
発行部数4
DOI
出版物ステータス出版済み - 5 19 2006

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

フィンガープリント CYLD in Ubiquitin Signaling and Tumor Pathogenesis' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用