CYLD in Ubiquitin Signaling and Tumor Pathogenesis

Fumiyo Ikeda, Ivan Dikic

研究成果: ジャーナルへの寄稿小調査

21 引用 (Scopus)

抄録

Absence of CYLD, which encodes a deubiquitinating enzyme, causes an inherited disease characterized by benign skin tumors. In this issue of Cell, Massoumi et al. (2006) show that CYLD deubiquitinates the coactivator Bcl-3, thereby preventing its translocation into the nucleus, where it normally interacts with NF-κB and activates transcription of proliferation genes in response to growth signals.

元の言語英語
ページ(範囲)643-645
ページ数3
ジャーナルCell
125
発行部数4
DOI
出版物ステータス出版済み - 5 19 2006

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Transcription
Ubiquitin
Tumors
Skin
Genes
Enzymes
Growth
Neoplasms
Deubiquitinating Enzymes

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

これを引用

CYLD in Ubiquitin Signaling and Tumor Pathogenesis. / Ikeda, Fumiyo; Dikic, Ivan.

:: Cell, 巻 125, 番号 4, 19.05.2006, p. 643-645.

研究成果: ジャーナルへの寄稿小調査

Ikeda, Fumiyo ; Dikic, Ivan. / CYLD in Ubiquitin Signaling and Tumor Pathogenesis. :: Cell. 2006 ; 巻 125, 番号 4. pp. 643-645.
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