Cytokines and chemokines in the epidermis

Hiroshi Uchi, Hiroshi Terao, Tetsuya Koga, Masutaka Furue

研究成果: Contribution to journalArticle査読

128 被引用数 (Scopus)

抄録

Keratinocytes (KC) produce a vast repertoire of cytokines, including interleukins, growth factors, colony stimulating factors, and chemokines. Under normal conditions, most of them are not synthesized or remain in the cytoplasm, but external stimuli, such as trauma, bacterial infections, chemical substances, or ultraviolet irradiation induce the production and release of these cytokines from KC. KC-derived cytokines regulate the immune and inflammatory responses through their receptors on KC, Langerhans cells, dermal fibroblasts and endothelial cells, and infiltrating T-cells.

本文言語英語
ページ(範囲)S29-S38
ジャーナルJournal of Dermatological Science
24
SUPPL. 1
DOI
出版ステータス出版済み - 2000

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Dermatology

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