Cytotoxic lavandulyl flavanones from Sophora flavescens

Tai Hyun Kang, Sei Joon Jeong, Won Gil Ko, Na Young Kim, Byung Hoon Lee, Masanori Inagaki, Tomofumi Miyamoto, Ryuichi Higuchi, Youn Chul Kim

研究成果: ジャーナルへの寄稿記事

104 引用 (Scopus)

抄録

Two new lavandulylated flavanones, (2S)-2'-methoxykurarinone (1) and (- )-kurarinone (2), were isolated from the root of Sophora flavescens, together with two known lavandulyl flavanones, sophoraflavanone G (3) and leachianone A (4), and two known isoflavonoids, formononetin and l-maakiain. The structures of 1 and 2 were determined on the basis of optical rotation and spectral evidence and by comparison with known compounds. Compounds 1-4 exhibited cytotoxic activity against human myeloid leukemia HL-60 cells.

元の言語英語
ページ(範囲)680-681
ページ数2
ジャーナルJournal of Natural Products
63
発行部数5
DOI
出版物ステータス出版済み - 5 1 2000

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Sophora
Flavanones
Optical rotation
Optical Rotation
Myeloid Leukemia
HL-60 Cells
Human Activities

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

これを引用

Kang, T. H., Jeong, S. J., Ko, W. G., Kim, N. Y., Lee, B. H., Inagaki, M., ... Kim, Y. C. (2000). Cytotoxic lavandulyl flavanones from Sophora flavescens. Journal of Natural Products, 63(5), 680-681. https://doi.org/10.1021/np990567x

Cytotoxic lavandulyl flavanones from Sophora flavescens. / Kang, Tai Hyun; Jeong, Sei Joon; Ko, Won Gil; Kim, Na Young; Lee, Byung Hoon; Inagaki, Masanori; Miyamoto, Tomofumi; Higuchi, Ryuichi; Kim, Youn Chul.

:: Journal of Natural Products, 巻 63, 番号 5, 01.05.2000, p. 680-681.

研究成果: ジャーナルへの寄稿記事

Kang, TH, Jeong, SJ, Ko, WG, Kim, NY, Lee, BH, Inagaki, M, Miyamoto, T, Higuchi, R & Kim, YC 2000, 'Cytotoxic lavandulyl flavanones from Sophora flavescens', Journal of Natural Products, 巻. 63, 番号 5, pp. 680-681. https://doi.org/10.1021/np990567x
Kang TH, Jeong SJ, Ko WG, Kim NY, Lee BH, Inagaki M その他. Cytotoxic lavandulyl flavanones from Sophora flavescens. Journal of Natural Products. 2000 5 1;63(5):680-681. https://doi.org/10.1021/np990567x
Kang, Tai Hyun ; Jeong, Sei Joon ; Ko, Won Gil ; Kim, Na Young ; Lee, Byung Hoon ; Inagaki, Masanori ; Miyamoto, Tomofumi ; Higuchi, Ryuichi ; Kim, Youn Chul. / Cytotoxic lavandulyl flavanones from Sophora flavescens. :: Journal of Natural Products. 2000 ; 巻 63, 番号 5. pp. 680-681.
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abstract = "Two new lavandulylated flavanones, (2S)-2'-methoxykurarinone (1) and (- )-kurarinone (2), were isolated from the root of Sophora flavescens, together with two known lavandulyl flavanones, sophoraflavanone G (3) and leachianone A (4), and two known isoflavonoids, formononetin and l-maakiain. The structures of 1 and 2 were determined on the basis of optical rotation and spectral evidence and by comparison with known compounds. Compounds 1-4 exhibited cytotoxic activity against human myeloid leukemia HL-60 cells.",
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