Cytotoxic lavandulyl flavanones from Sophora flavescens

Tai Hyun Kang, Sei Joon Jeong, Won Gil Ko, Na Young Kim, Byung Hoon Lee, Masanori Inagaki, Tomofumi Miyamoto, Ryuichi Higuchi, Youn Chul Kim

研究成果: Contribution to journalArticle査読

122 被引用数 (Scopus)

抄録

Two new lavandulylated flavanones, (2S)-2'-methoxykurarinone (1) and (- )-kurarinone (2), were isolated from the root of Sophora flavescens, together with two known lavandulyl flavanones, sophoraflavanone G (3) and leachianone A (4), and two known isoflavonoids, formononetin and l-maakiain. The structures of 1 and 2 were determined on the basis of optical rotation and spectral evidence and by comparison with known compounds. Compounds 1-4 exhibited cytotoxic activity against human myeloid leukemia HL-60 cells.

本文言語英語
ページ(範囲)680-681
ページ数2
ジャーナルJournal of Natural Products
63
5
DOI
出版ステータス出版済み - 5 2000

All Science Journal Classification (ASJC) codes

  • 分析化学
  • 分子医療
  • 薬理学
  • 薬科学
  • 創薬
  • 補完代替医療
  • 有機化学

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