TY - JOUR
T1 - Cytotoxin-converting phages, φCTX and PS21, are R pyocin-related phages
AU - Hayashi, Tetsuya
AU - Matsumoto, Hideki
AU - Ohnishi, Makoto
AU - Yokota, Shin ichi
AU - Shinomiya, Tomoyuki
AU - Kageyama, Makoto
AU - Terawaki, Yoshiro
N1 - Funding Information:
tance. This work was supported by a Grant-in-Aid for Scientific Research from Ministry of Education, Science and Culture of Japan.
PY - 1994/10/1
Y1 - 1994/10/1
N2 - φCTX is a temperate phage of Pseudomonas aeruginosa harbouring the ctx gene that encodes cytotoxin (CTX). We identified φCTX as an R pyocin-related phage, by serological and molecular analysis, based on the findings that the infectivity of the phage was inhibited with the antisera directed R pyocins and R pyocin-related phages and that the φCTX genome showed DNA homology to the genome of PS17 (a representative of the R pyocin-related phages) as well as to the pyocin R2 genes. Another new CTX-converting, R pyocin-related phage named PS21 was isolated from a CTX-producing strain of P. aeruginosa, suggesting the distribution of the ctx gene by certain members of R pyocin-related phage family.
AB - φCTX is a temperate phage of Pseudomonas aeruginosa harbouring the ctx gene that encodes cytotoxin (CTX). We identified φCTX as an R pyocin-related phage, by serological and molecular analysis, based on the findings that the infectivity of the phage was inhibited with the antisera directed R pyocins and R pyocin-related phages and that the φCTX genome showed DNA homology to the genome of PS17 (a representative of the R pyocin-related phages) as well as to the pyocin R2 genes. Another new CTX-converting, R pyocin-related phage named PS21 was isolated from a CTX-producing strain of P. aeruginosa, suggesting the distribution of the ctx gene by certain members of R pyocin-related phage family.
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U2 - 10.1111/j.1574-6968.1994.tb07174.x
DO - 10.1111/j.1574-6968.1994.tb07174.x
M3 - Article
C2 - 7988867
AN - SCOPUS:0028167864
SN - 0378-1097
VL - 122
SP - 239
EP - 344
JO - FEMS Microbiology Letters
JF - FEMS Microbiology Letters
IS - 3
ER -