De novo malignancy after pancreas transplantation in Japan

Y. Tomimaru, T. Ito, S. Marubashi, K. Kawamoto, A. Tomokuni, T. Asaoka, H. Wada, H. Eguchi, M. Mori, Y. Doki, H. Nagano

研究成果: Contribution to journalArticle査読

5 被引用数 (Scopus)

抄録

Background Long-term immunosuppression is associated with an increased risk of cancer. Especially, the immunosuppression in pancreas transplantation is more intensive than that in other organ transplantation because of its strong immunogenicity. Therefore, it suggests that the risk of post-transplant de novo malignancy might increase in pancreas transplantation. However, there have been few studies of de novo malignancy after pancreas transplantation. The aim of this study was to analyze the incidence of de novo malignancy after pancreas transplantation in Japan. Methods Post-transplant patients with de novo malignancy were surveyed and characterized in Japan. Results Among 107 cases receiving pancreas transplantation in Japan between 2001 and 2010, de novo malignancy developed in 9 cases (8.4%): post-transplant lymphoproliferative disorders in 6 cases, colon cancer in 1 case, renal cancer in 1 case, and brain tumor in 1 case. Conclusions We clarified the incidence of de novo malignancy after pancreas transplantation in Japan.

本文言語英語
ページ(範囲)742-745
ページ数4
ジャーナルTransplantation Proceedings
47
3
DOI
出版ステータス出版済み - 4 1 2015

All Science Journal Classification (ASJC) codes

  • Surgery
  • Transplantation

フィンガープリント 「De novo malignancy after pancreas transplantation in Japan」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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