Decay of linkage disequilibrium in a finite island model

Hidenori Tachida

研究成果: Contribution to journalArticle査読

4 被引用数 (Scopus)

抄録

Time-dependent behaviour of linkage disequilibrium when there was initial linkage disequilibrium is studied in a finite island model assuming neutrality. Explicit expressions for linkage disequilibrium parameters are obtained. From these expressions, the initial and the ultimate decay rates of linkage disequilibrium parameters are found to be increased and decreased, respectively, by finiteness of the population when recombination rate, migration rate and inverse of subpopulation size are of comparable order. Thus, linkage disequilibrium created in the past may persist longerin smaller subdivided populations. Also, differentiation of the gametic parameter of linkage disequilibrium among subpopulations is found to diminish quickly compared tothe linkage disequilibrium in the whole population. Implications of these results for the interpretation of linkage disequilibria in natural populations are discussed.

本文言語英語
ページ(範囲)137-144
ページ数8
ジャーナルGenetical Research
64
2
DOI
出版ステータス出版済み - 10 1994

All Science Journal Classification (ASJC) codes

  • 遺伝学

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