Decellularization of liver and organogenesis in rats

Nana Shirakigawa, Hiroyuki Ijima

研究成果: Chapter in Book/Report/Conference proceedingChapter

2 被引用数 (Scopus)

抄録

Recently, organ construction has been attempted using decellularized organs. In this study, we used decellularized rat liver to construct liver tissue by recellularization. The right lobe of the rat liver was decellularized with 4% Triton X-100 solution, recellularized with 107 rat hepatocytes, and albumin synthesis in the recellularized right lobe was observed. Therefore, we introduce a method of decellularizing rat liver, which retains its fine vascular structure after removal of all the cells, perform organogenesis using the decellularized liver, and evaluate the structural and functional properties of the products.

本文言語英語
ホスト出版物のタイトルMethods in Molecular Biology
出版社Humana Press Inc.
ページ271-281
ページ数11
DOI
出版ステータス出版済み - 1 1 2018

出版物シリーズ

名前Methods in Molecular Biology
1577
ISSN(印刷版)1064-3745

All Science Journal Classification (ASJC) codes

  • 分子生物学
  • 遺伝学

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