Decrease in bovine CD14 positive cells in colostrum is associated with the incidence of mastitis after calving

Yoshio Kiku, Tomomi Ozawa, Shiro Kushibiki, Madoka Sudo, Kouhei Kitazaki, Noriaki Abe, Hideyuki Takahashi, Tomohito Hayashi

研究成果: Contribution to journalArticle査読

10 被引用数 (Scopus)

抄録

During the postpartum period there is a high incidence of mastitis in dairy cows. The reason for this increased risk of mastitis still remains unclear. Since leukocytes in colostrum have an important role in preventing the onset of mastitis, we investigated the leukocyte populations, which express CD4, CD8, CD14, CD21 or WC1, in colostrum as well as in blood obtained from 14 Holstein cows. Eight cows developed mastitis within a week after calving and the other 6 remained healthy. The percentage of CD14+ cells in colostrum was significantly lower in mastitic cows than in healthy cows. There were no significant differences in other marker positive cells either in the colostrum or in the blood. The CD14+ cells in colostrum play an important role of defense against invading microorganisms in the mammary glands. Our results suggested that the lower percentage of CD14+ cells in colostrum might predict the incidence of mastitis in the following period.

本文言語英語
ページ(範囲)197-203
ページ数7
ジャーナルVeterinary Research Communications
34
2
DOI
出版ステータス出版済み - 2 2010
外部発表はい

All Science Journal Classification (ASJC) codes

  • veterinary(all)

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