Dehydroepiandrosterone(DHEA)and bone metabolism

研究成果: Contribution to journalReview article査読

2 被引用数 (Scopus)

抄録

Dehydroepiandrosterone(DHEA), an adrenal androgen, has attracted much attention as an anti-aging hormone as well as a marker for senescence because of its unique change along with aging. DHEA is reported to have beneficial effects such as anti-diabetes, anti-obesity, and anti-atherosclerosis. It is also shown that DHEA has anti-osteoporosis effects to increase bone mineral density in randomized controlled trials(RCTs). As osteoblasts express aromatase which will convert androgen to estrogen, DHEA may act protectively against osteoporosis through its metabolites. Because there is no report on fracture risk by DHEA administration, further studies are required to clarify DHEA effects on human bone metabolism.

本文言語英語
ページ(範囲)987-993
ページ数7
ジャーナルClinical calcium
26
7
出版ステータス出版済み - 7 1 2016
外部発表はい

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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