TY - JOUR
T1 - Demographics, management and treatment outcomes of benign and malignant retroperitoneal tumors in Japan
AU - the Kyushu Cooperative Urological Research Group
AU - Fujimoto, Naohiro
AU - Kubo, Tatsuhiko
AU - Hisaoka, Masanori
AU - Udo, Kazuma
AU - Yokomizo, Akira
AU - Shibuya, Tadamasa
AU - Wakeda, Hironobu
AU - Nishihara, Kiyoaki
AU - Moriya, Ryosuke
AU - Iwakuma, Keiko
AU - Eto, Masatoshi
AU - Naito, Seiji
AU - Furuya, Ryusaburo
AU - Tanaka, Masatoshi
AU - Ishii, Tatsu
AU - Igawa, Tsukasa
AU - Noguchi, Mitsuru
AU - Takehara, Kosuke
AU - Hakariya, Tomoaki
AU - Sakai, Hideki
AU - Mimata, Hiromitsu
AU - Kawano, Yoshiaki
AU - Kamba, Tomomi
AU - Kamoto, Toshiyuki
AU - Yamane, Takashi
AU - Nakagawa, Masayuki
AU - Oshiro, Yoshinori
AU - Ashimine, Satoshi
AU - Saito, Seiichi
N1 - Publisher Copyright:
© 2017 The Authors. International Journal of Urology published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Urological Association.
PY - 2018/1
Y1 - 2018/1
N2 - Objectives: To show the demographics, type of treatment and clinical outcomes of patients with retroperitoneal tumors in Japan. Methods: We carried out a retrospective analysis of patients with retroperitoneal tumors treated between 2000 and 2012 at 12 university hospitals in Japan. Histology was re-evaluated using the 2013 World Health Organization classification. Results: A total of 167 patients were included in the analysis. The number of diagnosed patients increased over the 12-year study period. Liposarcoma and schwannoma were the most common histological types among intermediate/malignant and benign tumors, respectively. The intermediate/malignant tumors were larger and were more frequently found in older people. Surgical resection was the primary treatment for 151 patients. The median survival duration for patients with malignant tumors was 91 months, and was significantly shorter than that for patients with benign and intermediate tumors (P < 0.01). R2 resection was associated with significantly shorter survival than R0/R1 resection for malignant tumors (P < 0.01), but not for intermediate. Grossly complete resection of the recurrent tumors improved survival. Conclusion: The number of patients diagnosed with retroperitoneal tumors increased over time. R2 resection of primary tumors was found to be associated with poor prognosis in malignant tumors, but not in intermediate tumors. Complete surgical resection of recurrent tumors was associated with a better oncological outcome.
AB - Objectives: To show the demographics, type of treatment and clinical outcomes of patients with retroperitoneal tumors in Japan. Methods: We carried out a retrospective analysis of patients with retroperitoneal tumors treated between 2000 and 2012 at 12 university hospitals in Japan. Histology was re-evaluated using the 2013 World Health Organization classification. Results: A total of 167 patients were included in the analysis. The number of diagnosed patients increased over the 12-year study period. Liposarcoma and schwannoma were the most common histological types among intermediate/malignant and benign tumors, respectively. The intermediate/malignant tumors were larger and were more frequently found in older people. Surgical resection was the primary treatment for 151 patients. The median survival duration for patients with malignant tumors was 91 months, and was significantly shorter than that for patients with benign and intermediate tumors (P < 0.01). R2 resection was associated with significantly shorter survival than R0/R1 resection for malignant tumors (P < 0.01), but not for intermediate. Grossly complete resection of the recurrent tumors improved survival. Conclusion: The number of patients diagnosed with retroperitoneal tumors increased over time. R2 resection of primary tumors was found to be associated with poor prognosis in malignant tumors, but not in intermediate tumors. Complete surgical resection of recurrent tumors was associated with a better oncological outcome.
UR - http://www.scopus.com/inward/record.url?scp=85040643850&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85040643850&partnerID=8YFLogxK
U2 - 10.1111/iju.13469
DO - 10.1111/iju.13469
M3 - Article
C2 - 28994196
AN - SCOPUS:85040643850
VL - 25
SP - 61
EP - 67
JO - International Journal of Urology
JF - International Journal of Urology
SN - 0919-8172
IS - 1
ER -