Dependency on light and vitamin a derivatives of the biogenesis of 3-hydroxyretinal and visual pigment in the compound eyes of Drosophila melanogaster

Kunio Isono, Teiichi Tanimura, Yoshiharu Oda, Yasuo Tsukahara

研究成果: ジャーナルへの寄稿記事

39 引用 (Scopus)

抄録

When the fruitfly, Drosophila rtwlanogaster, was reared on media deficient in carotenoids and retinoids, the level of 3-hydroxyretinal (the chromophore of fly rhodopsin) in the retina decreased to < 1% compared with normal flies. The level of 3-hydroxyretinal increased markedly in flies that were given a diet supplemented with retinoids or carotenoids. The retinas of flies fed on all tram retinoids and maintained in the dark predominantly contained the all-tram form of 3-hydroxyretinal, and showed no increase in the level of either the 11-c/s isomer or the visual pigment. Subsequent illumination of the flies converted substantial amounts of all-tram 3-hydroxyretinal to its 11-c/s isomer. The action spectrum of the conversion by illumination showed the optimum wavelength to be ~420 nm, which is significantly greater than the absorption maximum of free, all-tram 3-hydrox), retinal. Flies that were fed on carotenoids showed a rapid increase of the levels of 11-cis 3-hydroxyretinal and of visual pigment in the absence of light.

元の言語英語
ページ(範囲)587-600
ページ数14
ジャーナルJournal of General Physiology
92
発行部数5
DOI
出版物ステータス出版済み - 11 1 1988

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Retinal Pigments
Drosophila melanogaster
Vitamins
Diptera
Light
Retinoids
Carotenoids
Lighting
Retina
Rhodopsin
Drosophila
3-hydroxyretinal
Diet

All Science Journal Classification (ASJC) codes

  • Physiology

これを引用

Dependency on light and vitamin a derivatives of the biogenesis of 3-hydroxyretinal and visual pigment in the compound eyes of Drosophila melanogaster. / Isono, Kunio; Tanimura, Teiichi; Oda, Yoshiharu; Tsukahara, Yasuo.

:: Journal of General Physiology, 巻 92, 番号 5, 01.11.1988, p. 587-600.

研究成果: ジャーナルへの寄稿記事

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abstract = "When the fruitfly, Drosophila rtwlanogaster, was reared on media deficient in carotenoids and retinoids, the level of 3-hydroxyretinal (the chromophore of fly rhodopsin) in the retina decreased to < 1{\%} compared with normal flies. The level of 3-hydroxyretinal increased markedly in flies that were given a diet supplemented with retinoids or carotenoids. The retinas of flies fed on all tram retinoids and maintained in the dark predominantly contained the all-tram form of 3-hydroxyretinal, and showed no increase in the level of either the 11-c/s isomer or the visual pigment. Subsequent illumination of the flies converted substantial amounts of all-tram 3-hydroxyretinal to its 11-c/s isomer. The action spectrum of the conversion by illumination showed the optimum wavelength to be ~420 nm, which is significantly greater than the absorption maximum of free, all-tram 3-hydrox), retinal. Flies that were fed on carotenoids showed a rapid increase of the levels of 11-cis 3-hydroxyretinal and of visual pigment in the absence of light.",
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AU - Tsukahara, Yasuo

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N2 - When the fruitfly, Drosophila rtwlanogaster, was reared on media deficient in carotenoids and retinoids, the level of 3-hydroxyretinal (the chromophore of fly rhodopsin) in the retina decreased to < 1% compared with normal flies. The level of 3-hydroxyretinal increased markedly in flies that were given a diet supplemented with retinoids or carotenoids. The retinas of flies fed on all tram retinoids and maintained in the dark predominantly contained the all-tram form of 3-hydroxyretinal, and showed no increase in the level of either the 11-c/s isomer or the visual pigment. Subsequent illumination of the flies converted substantial amounts of all-tram 3-hydroxyretinal to its 11-c/s isomer. The action spectrum of the conversion by illumination showed the optimum wavelength to be ~420 nm, which is significantly greater than the absorption maximum of free, all-tram 3-hydrox), retinal. Flies that were fed on carotenoids showed a rapid increase of the levels of 11-cis 3-hydroxyretinal and of visual pigment in the absence of light.

AB - When the fruitfly, Drosophila rtwlanogaster, was reared on media deficient in carotenoids and retinoids, the level of 3-hydroxyretinal (the chromophore of fly rhodopsin) in the retina decreased to < 1% compared with normal flies. The level of 3-hydroxyretinal increased markedly in flies that were given a diet supplemented with retinoids or carotenoids. The retinas of flies fed on all tram retinoids and maintained in the dark predominantly contained the all-tram form of 3-hydroxyretinal, and showed no increase in the level of either the 11-c/s isomer or the visual pigment. Subsequent illumination of the flies converted substantial amounts of all-tram 3-hydroxyretinal to its 11-c/s isomer. The action spectrum of the conversion by illumination showed the optimum wavelength to be ~420 nm, which is significantly greater than the absorption maximum of free, all-tram 3-hydrox), retinal. Flies that were fed on carotenoids showed a rapid increase of the levels of 11-cis 3-hydroxyretinal and of visual pigment in the absence of light.

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