Design and fabrication of air-flow based single particle dispensing system

Tomohiro Kawahara, Shigeo Ohashi, Masaya Hagiwara, Yoko Yamanishi, Fumihito Arai

研究成果: 著書/レポートタイプへの貢献会議での発言

4 引用 (Scopus)

抄録

In this paper, we discuss the design and fabrication approach to increase the success rate of single particle dispensing. Two pairs of capacitance sensors are placed in a biochip to detect the flow velocity of particles, and the air pressure is applied to eject particles by synchronizing the timing. Comprehensive design theory, which is taken into account of the back pressure caused by air pressure, the response time of the system, sensor property, and the delay of the dispensing from the air pressure, is developed in order to minimize the disturbance of the system and maximize the throughput of the ejection system. Then, the system has capability to eject 3 particles/sec and maximum flow velocity is 10 mm/s. The novelty of the system is that the biochip is disposable which is unlike the conventional mechanical inkjet system and it can prevent contamination. Therefore, the fabricated disposable biochip based on photolithography is low cost and the drive system is reusable. Finally, we succeed in automatic dispensing of a single particle (=100 μm) from a biochip to culture well atmosphere using developed cell ejection system with the success rate of 50 %.

元の言語英語
ホスト出版物のタイトルIROS'11 - 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems
ホスト出版物のサブタイトルCelebrating 50 Years of Robotics
出版者Institute of Electrical and Electronics Engineers Inc.
ページ1309-1314
ページ数6
ISBN(印刷物)9781612844541
DOI
出版物ステータス出版済み - 1 1 2011
イベント2011 IEEE/RSJ International Conference on Intelligent Robots and Systems: Celebrating 50 Years of Robotics, IROS'11 - San Francisco, CA, 米国
継続期間: 9 25 20119 30 2011

出版物シリーズ

名前IEEE International Conference on Intelligent Robots and Systems
ISSN(印刷物)2153-0858
ISSN(電子版)2153-0866

その他

その他2011 IEEE/RSJ International Conference on Intelligent Robots and Systems: Celebrating 50 Years of Robotics, IROS'11
米国
San Francisco, CA
期間9/25/119/30/11

Fingerprint

Biochips
Fabrication
Air
Flow velocity
Sensors
Photolithography
Contamination
Capacitance
Throughput
Costs

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering
  • Software
  • Computer Vision and Pattern Recognition
  • Computer Science Applications

これを引用

Kawahara, T., Ohashi, S., Hagiwara, M., Yamanishi, Y., & Arai, F. (2011). Design and fabrication of air-flow based single particle dispensing system. : IROS'11 - 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems: Celebrating 50 Years of Robotics (pp. 1309-1314). [6048514] (IEEE International Conference on Intelligent Robots and Systems). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/IROS.2011.6048514

Design and fabrication of air-flow based single particle dispensing system. / Kawahara, Tomohiro; Ohashi, Shigeo; Hagiwara, Masaya; Yamanishi, Yoko; Arai, Fumihito.

IROS'11 - 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems: Celebrating 50 Years of Robotics. Institute of Electrical and Electronics Engineers Inc., 2011. p. 1309-1314 6048514 (IEEE International Conference on Intelligent Robots and Systems).

研究成果: 著書/レポートタイプへの貢献会議での発言

Kawahara, T, Ohashi, S, Hagiwara, M, Yamanishi, Y & Arai, F 2011, Design and fabrication of air-flow based single particle dispensing system. : IROS'11 - 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems: Celebrating 50 Years of Robotics., 6048514, IEEE International Conference on Intelligent Robots and Systems, Institute of Electrical and Electronics Engineers Inc., pp. 1309-1314, 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems: Celebrating 50 Years of Robotics, IROS'11, San Francisco, CA, 米国, 9/25/11. https://doi.org/10.1109/IROS.2011.6048514
Kawahara T, Ohashi S, Hagiwara M, Yamanishi Y, Arai F. Design and fabrication of air-flow based single particle dispensing system. : IROS'11 - 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems: Celebrating 50 Years of Robotics. Institute of Electrical and Electronics Engineers Inc. 2011. p. 1309-1314. 6048514. (IEEE International Conference on Intelligent Robots and Systems). https://doi.org/10.1109/IROS.2011.6048514
Kawahara, Tomohiro ; Ohashi, Shigeo ; Hagiwara, Masaya ; Yamanishi, Yoko ; Arai, Fumihito. / Design and fabrication of air-flow based single particle dispensing system. IROS'11 - 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems: Celebrating 50 Years of Robotics. Institute of Electrical and Electronics Engineers Inc., 2011. pp. 1309-1314 (IEEE International Conference on Intelligent Robots and Systems).
@inproceedings{a53d470279a6481a9c99b519de486918,
title = "Design and fabrication of air-flow based single particle dispensing system",
abstract = "In this paper, we discuss the design and fabrication approach to increase the success rate of single particle dispensing. Two pairs of capacitance sensors are placed in a biochip to detect the flow velocity of particles, and the air pressure is applied to eject particles by synchronizing the timing. Comprehensive design theory, which is taken into account of the back pressure caused by air pressure, the response time of the system, sensor property, and the delay of the dispensing from the air pressure, is developed in order to minimize the disturbance of the system and maximize the throughput of the ejection system. Then, the system has capability to eject 3 particles/sec and maximum flow velocity is 10 mm/s. The novelty of the system is that the biochip is disposable which is unlike the conventional mechanical inkjet system and it can prevent contamination. Therefore, the fabricated disposable biochip based on photolithography is low cost and the drive system is reusable. Finally, we succeed in automatic dispensing of a single particle (=100 μm) from a biochip to culture well atmosphere using developed cell ejection system with the success rate of 50 {\%}.",
author = "Tomohiro Kawahara and Shigeo Ohashi and Masaya Hagiwara and Yoko Yamanishi and Fumihito Arai",
year = "2011",
month = "1",
day = "1",
doi = "10.1109/IROS.2011.6048514",
language = "English",
isbn = "9781612844541",
series = "IEEE International Conference on Intelligent Robots and Systems",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "1309--1314",
booktitle = "IROS'11 - 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems",
address = "United States",

}

TY - GEN

T1 - Design and fabrication of air-flow based single particle dispensing system

AU - Kawahara, Tomohiro

AU - Ohashi, Shigeo

AU - Hagiwara, Masaya

AU - Yamanishi, Yoko

AU - Arai, Fumihito

PY - 2011/1/1

Y1 - 2011/1/1

N2 - In this paper, we discuss the design and fabrication approach to increase the success rate of single particle dispensing. Two pairs of capacitance sensors are placed in a biochip to detect the flow velocity of particles, and the air pressure is applied to eject particles by synchronizing the timing. Comprehensive design theory, which is taken into account of the back pressure caused by air pressure, the response time of the system, sensor property, and the delay of the dispensing from the air pressure, is developed in order to minimize the disturbance of the system and maximize the throughput of the ejection system. Then, the system has capability to eject 3 particles/sec and maximum flow velocity is 10 mm/s. The novelty of the system is that the biochip is disposable which is unlike the conventional mechanical inkjet system and it can prevent contamination. Therefore, the fabricated disposable biochip based on photolithography is low cost and the drive system is reusable. Finally, we succeed in automatic dispensing of a single particle (=100 μm) from a biochip to culture well atmosphere using developed cell ejection system with the success rate of 50 %.

AB - In this paper, we discuss the design and fabrication approach to increase the success rate of single particle dispensing. Two pairs of capacitance sensors are placed in a biochip to detect the flow velocity of particles, and the air pressure is applied to eject particles by synchronizing the timing. Comprehensive design theory, which is taken into account of the back pressure caused by air pressure, the response time of the system, sensor property, and the delay of the dispensing from the air pressure, is developed in order to minimize the disturbance of the system and maximize the throughput of the ejection system. Then, the system has capability to eject 3 particles/sec and maximum flow velocity is 10 mm/s. The novelty of the system is that the biochip is disposable which is unlike the conventional mechanical inkjet system and it can prevent contamination. Therefore, the fabricated disposable biochip based on photolithography is low cost and the drive system is reusable. Finally, we succeed in automatic dispensing of a single particle (=100 μm) from a biochip to culture well atmosphere using developed cell ejection system with the success rate of 50 %.

UR - http://www.scopus.com/inward/record.url?scp=84455195581&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84455195581&partnerID=8YFLogxK

U2 - 10.1109/IROS.2011.6048514

DO - 10.1109/IROS.2011.6048514

M3 - Conference contribution

AN - SCOPUS:84455195581

SN - 9781612844541

T3 - IEEE International Conference on Intelligent Robots and Systems

SP - 1309

EP - 1314

BT - IROS'11 - 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems

PB - Institute of Electrical and Electronics Engineers Inc.

ER -