Design of a novel artificial nucleobase for the selective formation of a triple-complex with a cytosine-guanine base pair

Shigeki Sasaki, Shouji Nakashima, Fumi Nagatsugi, Yoshitsugu Tanaka, Masao Hisatome, Minoru Maeda

研究成果: Contribution to journalArticle査読

29 被引用数 (Scopus)

抄録

A new artificial nucleobase (1) was designed for the selective formation of a triple-complex with a cytosine-guanine base pair at the major groove site. It has been proved based on the 1D- and 2D 1H-NMR spectra that the protected 2′-oxy-1 (7) forms a triplex complex with the GC pair selectively.

本文言語英語
ページ(範囲)9521-9524
ページ数4
ジャーナルTetrahedron Letters
36
52
DOI
出版ステータス出版済み - 12 25 1995

All Science Journal Classification (ASJC) codes

  • 生化学
  • 創薬
  • 有機化学

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