抄録
Application of porous polymer materials to novel bio-interfaces for tissue engineering scaffold and artificial organs including blood filters, dialyzer, and oxygenator membranes have been in progress. The present study describes the fabrication and characterization of self-organized highly regular porous polymer films with uniform pore sizes are prepared by simple casting technique. Various fabrication parameters affecting the pore size such as polymer concentration, boiling point of solvent, cast volume and substrate are studied. The pore size can be controlled in the range from 1 to 50 μm by changing the evaporation rate of the polymer solutions. The porous film with uniform pore size is used for tissue engineering scaffold and cell separation membrane. To simulate the leukocyte eliminating from human blood, the porous film was attached to a module. The films with 5-9 μm pores provided the complete selectivity of separation for the leukocyte from the whole blood. The leukocyte elimination ratio depends on pore structures (size and depth) as well as recovery of platelet and erythrocyte.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 439-446 |
| ページ数 | 8 |
| ジャーナル | Bio-Medical Materials and Engineering |
| 巻 | 14 |
| 発行部数 | 4 |
| 出版物ステータス | 出版済み - 12 1 2004 |
| 外部発表 | Yes |
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All Science Journal Classification (ASJC) codes
- Biomaterials
- Biomedical Engineering
これを引用
Design of novel biointerfaces (II). Fabrication of self-organized porous polymer film with highly uniform pores. / Tanaka, Masaru; Takebayashi, Masafumi; Miyama, Masashi; Nishida, Jin; Shimomura, Masatsugu.
：: Bio-Medical Materials and Engineering, 巻 14, 番号 4, 01.12.2004, p. 439-446.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - Design of novel biointerfaces (II). Fabrication of self-organized porous polymer film with highly uniform pores
AU - Tanaka, Masaru
AU - Takebayashi, Masafumi
AU - Miyama, Masashi
AU - Nishida, Jin
AU - Shimomura, Masatsugu
PY - 2004/12/1
Y1 - 2004/12/1
N2 - Application of porous polymer materials to novel bio-interfaces for tissue engineering scaffold and artificial organs including blood filters, dialyzer, and oxygenator membranes have been in progress. The present study describes the fabrication and characterization of self-organized highly regular porous polymer films with uniform pore sizes are prepared by simple casting technique. Various fabrication parameters affecting the pore size such as polymer concentration, boiling point of solvent, cast volume and substrate are studied. The pore size can be controlled in the range from 1 to 50 μm by changing the evaporation rate of the polymer solutions. The porous film with uniform pore size is used for tissue engineering scaffold and cell separation membrane. To simulate the leukocyte eliminating from human blood, the porous film was attached to a module. The films with 5-9 μm pores provided the complete selectivity of separation for the leukocyte from the whole blood. The leukocyte elimination ratio depends on pore structures (size and depth) as well as recovery of platelet and erythrocyte.
AB - Application of porous polymer materials to novel bio-interfaces for tissue engineering scaffold and artificial organs including blood filters, dialyzer, and oxygenator membranes have been in progress. The present study describes the fabrication and characterization of self-organized highly regular porous polymer films with uniform pore sizes are prepared by simple casting technique. Various fabrication parameters affecting the pore size such as polymer concentration, boiling point of solvent, cast volume and substrate are studied. The pore size can be controlled in the range from 1 to 50 μm by changing the evaporation rate of the polymer solutions. The porous film with uniform pore size is used for tissue engineering scaffold and cell separation membrane. To simulate the leukocyte eliminating from human blood, the porous film was attached to a module. The films with 5-9 μm pores provided the complete selectivity of separation for the leukocyte from the whole blood. The leukocyte elimination ratio depends on pore structures (size and depth) as well as recovery of platelet and erythrocyte.
UR - http://www.scopus.com/inward/record.url?scp=14044269931&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=14044269931&partnerID=8YFLogxK
M3 - Article
C2 - 15472392
AN - SCOPUS:14044269931
VL - 14
SP - 439
EP - 446
JO - Bio-Medical Materials and Engineering
JF - Bio-Medical Materials and Engineering
SN - 0959-2989
IS - 4
ER -